Home > Drug >

Zykadia

Zykadia

(ceritinib)

Zykadia (Ceritinib) belongs to the group of cancer-fighting medications known as antineoplastics and more specifically to a class of medications called protein kinase inhibitors. These medications slow the growth of blood vessels that feed nutrients to cancer cells.

Available form

Dosage

Capsule

150MG

Buy Zykadia Full drug details

What is Pocketpills?

As Canada's leading online pharmacy, we make sure you always have your meds on time. Use our app and website to fill prescriptions, order refills, and consult with our pharmacists. Take control of your health from home or on the go!

Easy refills, renewals, and reminders
Quick answers to your questions
Free delivery with SMS updates

Join us

We'd love to tell you more

We won't bore you with the details, but Health Canada requires you to sign in.

By proceeding you agree to our Terms of Use & Privacy Policy

Zykadia information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The usual recommended dose of Zykadia (Ceritinib) is 450 mg (3 × 150 mg capsules) taken by mouth once a day. Take Zykadia (Ceritinib) at the same time each day. Your doctor may adjust your dose depending on how you tolerate Zykadia (Ceritinib). Swallow the capsules whole – do not crush, dissolve, or open them.

Zykadia (Ceritinib) must be taken with food. This can be either a full meal or a snack. Do not take Zykadia (Ceritinib) with grapefruit, starfruit, pomegranate, Seville oranges, or other similar fruits, since they may interact with Zykadia (Ceritinib).

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Zykadia (Ceritinib) exactly as prescribed by your doctor.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is less than 12 hours until your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Zykadia (Ceritinib) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Zykadia (Ceritinib). If you are concerned about side effects, discuss the risks and benefits of Zykadia (Ceritinib) with your doctor.

The following side effects have been reported by at least 1% of people taking Zykadia (Ceritinib). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

abdominal pain
Constipation
decreased appetite
Diarrhea
headache
heartburn
low heart rate
nausea
rash
symptoms of Neuropathy (e.g., numbness, prickling or tingling, burning, freezing, throbbing and/or shooting pain in the hands and or feet)
tiredness
vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

chest pain
Fever
heart rhythm abnormality (e.g., dizziness, fainting, or chest discomfort)
Low Blood Pressure
pounding heartbeat
severe nausea, vomiting or diarrhea
signs of Anemia (low red blood cells; e.g., dizziness, pale skin, unusual tiredness or weakness, shortness of breath)
slow heart rate
symptoms of high blood sugar (e.g., frequent urination, hunger, thirst)
symptoms of kidney problems (e.g., pain in the back or side, blood in the urine)

symptoms of liver problems (e.g., feeling more tired than usual, decreased appetite, yellowing of the skin or whites of the eyes, stomach pain, dark urine, nausea, vomiting, itching, or bleeding or bruising more easily than normal)
symptoms of low levels of phosphate in the blood (e.g., muscle pain and weakness, change in mental state)
symptoms of lung infection or inflammation (e.g., difficulty breathing, cough, or fever)
vision changes (e.g., blurred vision, flashes of light, double vision)

Stop taking the medication and seek immediate medical attention if any of the following occur:

seizures
signs of bleeding in the stomach or digestive system (e.g., bloody, black or tarry stools, spitting up blood, vomiting blood or material that looks like coffee grounds)
signs of fluid buildup around the heart (e.g., chest pain or pressure, shortness of breath, nausea, difficulty swallowing)
signs of inflammation of the heart muscle (e.g., sharp stabbing chest pain that becomes worse with cough, swallowing, breathing, laying flat)
signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, swollen abdomen)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Zykadia (Ceritinib).

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Zykadia (Ceritinib).

Abnormal heart rhythms: Zykadia (Ceritinib) can cause abnormal heart rhythms. Certain medications (e.g., Sotalol, quinidine, thioridazine, Chlorpromazine, droperidol, Pimozide, moxifloxacin, Mefloquine, pentamidine, arsenic trioxide, probucol, Tacrolimus) can increase the risk of a type of abnormal heart rhythm called QT prolongation and should not be used in combination with Zykadia (Ceritinib). You are more at risk for this type of abnormal heart rhythm and its complications if you:

are female
are older than 65 years of age
have a family history of sudden cardiac death
have a history of heart disease or abnormal heart rhythms
have a slow heart rate
have congenital prolongation of the QT interval
have Diabetes
have had a Stroke
have low potassium, magnesium, or calcium levels
have nutritional deficiencies

If you have heart disease and abnormal heart rhythms or are taking certain medications (e.g., Verapamil, atazanavir), discuss with your doctor how Zykadia (Ceritinib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zykadia (Ceritinib), and whether any special monitoring is needed.

Birth control: Use effective birth control while using Zykadia (Ceritinib), as Zykadia (Ceritinib) may harm the baby if used during pregnancy. Both men and women should use effective birth control (e.g., condoms, birth control pill) during treatment and for at least 90 days after treatment is finished. If you or your partner become pregnant while taking Zykadia (Ceritinib), contact your doctor immediately.

Diabetes: Zykadia (Ceritinib) can cause increases in blood sugars. If you have diabetes or a family history of diabetes, discuss with your doctor how Zykadia (Ceritinib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zykadia (Ceritinib), and whether any special monitoring is needed.

Heart problems: Zykadia (Ceritinib) can decrease heart rate, which may contribute to heart failure or worsen symptoms of heart disease. If you have heart disease such as Angina, Congestive Heart Failure, or arrhythmia, discuss with your doctor how Zykadia (Ceritinib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zykadia (Ceritinib), and whether any special monitoring is needed. If you experience a heart rate of less than 60 beats per minute, or frequently feel faint or dizzy, contact your doctor.

Kidney problems: If you have severe kidney problems, discuss with your doctor how Zykadia (Ceritinib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zykadia (Ceritinib), and whether any special monitoring is needed.

Liver function: Liver disease or reduced liver function may cause Zykadia (Ceritinib) to build up in the body, causing side effects. Zykadia (Ceritinib) may also reduce liver function and can cause severe liver problems. Your doctor will monitor your liver function with blood tests while you are taking Zykadia (Ceritinib). If you have liver problems, discuss with your doctor how Zykadia (Ceritinib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zykadia (Ceritinib), and whether any special monitoring is needed.

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Lung inflammation: Lung inflammation (interstitial lung disease) causing difficulty breathing has occurred rarely in some people taking Zykadia (Ceritinib). This complication can be serious and sometimes fatal. If you experience new or worsening shortness of breath or cough (with or without fever) at any time while you are taking Zykadia (Ceritinib), contact your doctor immediately.

Nerve problems: People taking Zykadia (Ceritinib) may experience symptoms of neuropathy (nerve damage) such as numbness, prickling or tingling, burning, freezing, and throbbing or shooting pain. Tell your doctor if you experience any of these symptoms.

Pancreatitis: Zykadia (Ceritinib) can cause the pancreas to become inflamed. If you have a history of pancreatitis, discuss with your doctor how Zykadia (Ceritinib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zykadia (Ceritinib), and whether any special monitoring is needed.

Report signs of pancreatitis such as abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, or swollen abdomen to your doctor immediately.

If you have a history of pancreatitis, gallstones, Alcoholism, or high triglycerides, you may be more at risk of experiencing this.

Unwanted effects of Zykadia (Ceritinib): Nausea, vomiting and diarrhea are commonly experienced by people using Zykadia (Ceritinib). If they are severe, talk to your doctor or pharmacist about medications that can be used to control these symptoms.

Pregnancy: The safety of Zykadia (Ceritinib) if used during pregnancy has not been determined. Zykadia (Ceritinib) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Zykadia (Ceritinib), contact your doctor immediately.

Breast-feeding: It is not known if Zykadia (Ceritinib) passes into breast milk. If you are a breast-feeding mother and are taking Zykadia (Ceritinib), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Zykadia (Ceritinib) have not been established for children.

Continue with Pocketpills

All material © 1996-2024 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

Helpful links

See these other medications
that relate to

FAQs

Do I need a valid prescription (Rx) to order prescription medication?

Yes, you need a valid prescription, or Rx for short, from a Canadian prescriber to purchase medication that requires a prescription. If you need a new prescription, please contact us and we can help connect you with a doctor or we will reach out to your doctor for a renewal.

How can I refill my medication?

We will gladly coordinate with your doctor and insurance company to make sure you never run out of the medication you need. Additionally, we will remind you when it's time to schedule a delivery for your refill. You can also opt into automatic refills online, in the app, or by calling us at 1-855-950-7225.

Is Pocketpills free? How much does it cost?

Yes, Pocketpills services are free! You only pay your portion of your copay, and there are no hidden delivery or service fees. We'll transfer your prescriptions from your old pharmacy, find savings, and hand-deliver your medications at no extra cost.

What insurance plans do you accept?

We accept all insurance plans and direct bill ODB, OHIP+, and PharmaCare.

How much is shipping cost For Zykadia in Canada?

Shipping cost for Zykadia to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Zykadia delivered to my home?

You could get Zykadia delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.