Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Busulfex (Busulfan).
Anemia: Busulfex (Busulfan) may cause low levels of red blood cells. If you experience symptoms of reduced red blood cell count (anemia) such as shortness of breath, feeling unusually tired, or pale skin, contact your doctor as soon as possible.
Blood clotting: Busulfex (Busulfan) can reduce the number of platelet cells in the blood. Platelets help the blood to clot, and a shortage could make you bleed more easily.
Tell your doctor about any signs that your blood is not clotting as quickly as usual. Symptoms include black and tarry stools, blood in the urine, easy bruising, or cuts that won't stop bleeding.
Fertility: Sterility may occur with the use of Busulfex (Busulfan). Talk to your doctor about options for preserving fertility for the future.
Infection: As well as killing cancer cells, Busulfex (Busulfan) can reduce the number of cells that fight infection in the body (white blood cells). If possible, avoid contact with people who have contagious infections. Tell your doctor immediately if you notice signs of an infection, such as fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness. Your doctor will do blood tests regularly to monitor the number of specific types of blood cells in your blood.
Liver: People taking Busulfex (Busulfan) may have changes in liver function that produce abnormal liver test results. It may also cause blockage of some of the small blood vessels in the liver. Your doctor will monitor you for this with blood tests. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Lung disease: Busulfex (Busulfan) may in rare cases cause a form of lung disease that develops after your treatment with Busulfex (Busulfan) has been is completed. Contact your doctor immediately if you develop a persistent cough, shortness of breath, or fever. Routine breathing tests may be required.
Other cancers: The use of Busulfex (Busulfan) may increase your risk of developing another type of cancer, such as leukemias and tumours. Discuss any concerns you may have with your doctor.
Seizures: High doses of Busulfex (Busulfan) can increase the risk of seizures. If you have a history of Epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how Busulfex (Busulfan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Busulfex (Busulfan), and whether any special monitoring is needed.
Pregnancy: There is a possibility of birth defects if either the father or mother is taking Busulfex (Busulfan) at the time of conception, or if it is taken during pregnancy. Effective birth control should be practiced while using Busulfex (Busulfan) and should be continued for 6 months after treatment with Busulfex (Busulfan) is complete. If you become pregnant while taking Busulfex (Busulfan), talk to your doctor immediately.
Breast-feeding: It is not known if Busulfex (Busulfan) passes into breast milk. If you are a breast-feeding mother and are taking Busulfex (Busulfan), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
