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Opsumit

Opsumit

(macitentan)

Opsumit (Macitentan) belongs to the class of medications called endothelin receptor antagonists. It is used alone and in combination with other medications to treat pulmonary arterial hypertension (PAH).

Available form

Dosage

Tablet

10MG

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Opsumit information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The recommended adult dose of Opsumit (Macitentan) is 10 mg taken once daily. Opsumit (Macitentan) may be taken with food or on an empty stomach. Swallow the tablets whole with some water. Do not crush, break or chew the tablets.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important that Opsumit (Macitentan) be taken exactly as prescribed by your doctor.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Opsumit (Macitentan) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Opsumit (Macitentan).

Anemia: Opsumit (Macitentan) may cause low levels of red blood cells. If you experience symptoms of reduced red blood cell count (anemia) such as shortness of breath, feeling unusually tired or pale skin, contact your doctor as soon as possible.

Kidney function: Kidney Disease or reduced kidney function may cause Opsumit (Macitentan) to build up in the body, causing side effects. If you have reduced kidney function or kidney disease, discuss with your doctor how Opsumit (Macitentan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Opsumit (Macitentan), and whether any special monitoring is needed.

Liver function: Opsumit (Macitentan) may reduce liver function. If you have liver problems, discuss with your doctor how Opsumit (Macitentan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Opsumit (Macitentan), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Opsumit (Macitentan). People with severely reduced liver function should not use Opsumit (Macitentan).

Pregnancy: Opsumit (Macitentan) may cause harm or death to the developing baby and mother if it is taken during pregnancy. Women must not become pregnant while taking Opsumit (Macitentan) or for at least one month after stopping the medication. Your doctor may routinely perform pregnancy tests while you are taking Opsumit (Macitentan) to confirm the safety of continuing to take Opsumit (Macitentan).

Women who may become pregnant must not take Opsumit (Macitentan) until pregnancy is ruled out. If you become pregnant while taking Opsumit (Macitentan), contact your doctor immediately.

Breast-feeding: It is not known if Opsumit (Macitentan) passes into breast milk. If you are a breast-feeding mother and are taking Opsumit (Macitentan), it may affect your baby. Women should not breast-feed while taking Opsumit (Macitentan).

Children: The safety and effectiveness of using Opsumit (Macitentan) have not been established for children less than 18 years of age.

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