Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Mifegymiso.
Asthma: People with breathing problems may experience increased difficulty breathing when taking misoprostol. It may decrease the effectiveness of corticosteroids or cause tightening of the airways. If you have asthma, discuss with your doctor how Mifegymiso may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Mifegymiso, and whether any special monitoring is needed.
Diabetes: The safety and effectiveness of Mifegymiso have not been studied for women with diabetes. Mifegymiso is not recommended for women with diabetes.
Heavy bleeding: Treatment with mifepristone - misoprostol usually results in vaginal bleeding. This is not proof that the pregnancy has been terminated. Complete termination of pregnancy is confirmed at your follow-up appointment with your doctor.
Heavy vaginal bleeding is described as bleeding heavily enough to soak through 2 full-size sanitary pads an hour for 2 hours in a row. This may be a sign that the medication has not worked completely. Contact your doctor immediately if you have heavy vaginal bleeding that lasts more than several hours.
Heart disease: The safety and effectiveness of Mifegymiso have not been established for women with heart disease. Mifegymiso is not recommended for women with heart disease. If you have risk factors for developing heart disease, discuss with your doctor how Mifegymiso may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Mifegymiso, and whether any special monitoring is needed.
High blood pressure: The safety and effectiveness of Mifegymiso have not been studied for women with high blood pressure. Mifegymiso is not recommended for women with high blood pressure.
Infection: Rarely, serious and possibly fatal bacterial infections have occurred after taking mifepristone - misoprostol. If you experience abdominal pain or a general feeling of illness more than 24 hours after taking misoprostol, contact your doctor immediately.
Kidney function: The safety and effectiveness of using Mifegymiso have not been determined for women with renal failure. Mifegymiso is not recommended for women with renal failure.
Liver function: The safety and effectiveness of using Mifegymiso have not been determined for women with liver failure. Mifegymiso is not recommended for women with liver failure.
Medical monitoring: It is important to have an appointment with your doctor 7 to 14 days after taking the mifepristone in the doctor's office. This will let your doctor confirm that your pregnancy has safely been terminated.
Seizures: Seizures have been reported with other medications that are similar to misoprostol. If you have a history of seizures, discuss with your doctor how Mifegymiso may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Mifegymiso, and whether any special monitoring is needed.
Treatment failure: Although Mifegymiso is generally effective, there is a possibility it will not work. Babies that are born after failed use of these medications are at an increased risk of birth defects.
Pregnancy: You can become pregnant immediately after using Mifegymiso, and Mifegymiso may cause harm to a developing baby. To decrease the chance of birth defects, avoid becoming pregnant before your next menstrual period.
To avoid becoming pregnant, start using birth control right away.
Breast-feeding: Mifepristone may pass into breast milk. Misoprostol does pass into breast milk. If you are a breast-feeding mother and take mifepristone - misoprostol, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding
Children: The safety and effectiveness of using Mifegymiso have not been established for children less than 15 years of age.
