Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Cyclomen (Danazol).
Altered hormone levels: Cyclomen (Danazol) treatment causes considerable changes in hormone levels and may result in such side effects as acne, weight gain, irregular menstrual patterns or no menstruation, and the development of male characteristics (see below). If these are bothersome, discuss your concerns with your doctor.
Blood clots: Cyclomen (Danazol) may increase the chance of blood clot formation, causing reduced blood flow to organs or the extremities.
If you have a history of clotting, you may be at increased risk of experiencing blood-clot-related problems such as Heart Attack, Stroke, or clots in the deep veins of your leg. Discuss with your doctor how Cyclomen (Danazol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Cyclomen (Danazol), and whether any special monitoring is needed.
If you experience symptoms such as sharp pain and swelling in the leg, difficulty breathing, chest pain, blurred vision, or difficulty speaking, contact your doctor immediately.
Breast Cancer: Cyclomen (Danazol) is not intended to treat symptoms of breast cancer. Before starting Cyclomen (Danazol) therapy for the treatment of fibrocystic breast disease, your doctor should exclude the possibility of breast cancer. Any nodules that do not decrease in size after 2 or 3 months should be discussed with your doctor.
Cholesterol levels: People taking Cyclomen (Danazol) may experience changes to their blood cholesterol levels. If you have abnormal cholesterol levels or a history of elevated cholesterol, discuss with your doctor how Cyclomen (Danazol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Cyclomen (Danazol), and whether any special monitoring is needed.
Development of male characteristics: Women should watch closely for the development of male characteristics such as hoarseness or deepening of the voice, clitoral thickening, and more than minimal growth of body hair. These effects may not be reversible. If these effects occur, contact your doctor to discuss further therapy.
Diabetes: Cyclomen (Danazol) may interfere with blood glucose control. People with diabetes should monitor their blood glucose closely and report any abnormalities to their doctor. Antidiabetes medications may need to be adjusted.
Heart disease and blood pressure: Cyclomen (Danazol) may cause fluid retention, increased blood pressure and possibly blood clots. If you have a history of blood clots, high blood pressure, or other heart disease, discuss with your doctor how Cyclomen (Danazol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Cyclomen (Danazol), and whether any special monitoring is needed.
Kidney function: If you have Kidney Disease or reduced kidney function, discuss with your doctor how Cyclomen (Danazol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Cyclomen (Danazol), and whether any special monitoring is needed. While you are taking Cyclomen (Danazol), your doctor may order blood tests to check how well your kidneys are working.
Liver function: Cyclomen (Danazol) can cause decreased liver function and may cause liver failure, when taken at normal doses. If you have liver disease or reduced liver function, discuss with your doctor how Cyclomen (Danazol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Cyclomen (Danazol), and whether any special monitoring is needed. While you are taking Cyclomen (Danazol), your doctor may order blood tests to check how well your liver is working.
If you experience signs of decreased liver function, such as nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, or pale stools, contact your doctor as soon as possible.
Migraine headache: People taking Cyclomen (Danazol) may experience increased migraine Headaches. If you experience migraine headaches while taking Cyclomen (Danazol), contact your doctor. People who experience migraine headaches before taking Cyclomen (Danazol) may experience an increase in the frequency of migraine headaches. If you experience migraine headaches, discuss with your doctor how Cyclomen (Danazol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Cyclomen (Danazol), and whether any special monitoring is needed.
Ovarian Cancer: Cyclomen (Danazol) may increase the risk of ovarian cancer in people treated for endometriosis.
Seizure disorder: Cyclomen (Danazol) may affect medications taken to control seizures. If you have Epilepsy or another seizure disorder, discuss with your doctor how Cyclomen (Danazol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Cyclomen (Danazol), and whether any special monitoring is needed.
Thyroid tests: Cyclomen (Danazol) may interfere with laboratory tests used to monitor thyroid function.
Pregnancy: If taken during pregnancy, Cyclomen (Danazol) may be harmful to the unborn child. Cyclomen (Danazol) should be started during menstruation and an effective nonhormonal method of birth control should be used while taking it. If you think you may be pregnant, stop taking Cyclomen (Danazol) and discuss the risks with your doctor.
Breast-feeding: Cyclomen (Danazol) may cause harm to an infant if it is taken by a breast-feeding mother. It must not be taken by women who are breast-feeding.
Children: The safety and effectiveness of Cyclomen (Danazol) have not been established for use by children.
