Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Selegiline.
Antidepressant medication: Severe reactions are possible when selegiline is combined with tricyclic antidepressants or serotonin reuptake inhibitors, medications used to treat depression. The combination of selegiline and antidepressants from these groups must be avoided. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, and changes in mental state including delirium and agitation. Coma and death are also possible.
If you take any of these medications or have taken antidepressants recently, discuss with your doctor how Selegiline may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Selegiline, and whether any special monitoring is needed.
Headache: If you experiencing a severe headache or other unusual symptoms while taking selegiline, report them to a doctor immediately.
Levodopa: Some people who take selegiline may experience a worsening of levodopa-associated side effects, such as unusual movements of the body. Report these effects to your doctor as soon as possible. Your doctor may help with these effects by reducing the dose of levodopa.
Liver function: People taking selegiline may have changes in liver function that produce abnormal liver test results. Your doctor may recommend regular liver tests while you are taking Selegiline.
Maximum dose: Do not exceed the recommended daily dose of 10 mg of selegiline.
Pregnancy: Selegiline should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Selegiline, contact your doctor immediately.
Breast-feeding: It is not known if selegiline passes into breast milk. If you are a breast-feeding mother and are taking Selegiline, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Selegiline have not been established for children.