Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Lolo.

Blood clots: Lolo may increase the chance of blood clot formation, causing reduction of blood flow to organs or the extremities.

If you have a history of clotting you may be at increased risk of experiencing blood clot-related problems such as heart attack, stroke, or clots in the deep veins of your leg. Discuss with your doctor how Lolo may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lolo, and whether any special monitoring is needed.

If you experience symptoms such as sharp pain and swelling in the leg, difficulty breathing, chest pain, blurred vision or difficulty speaking, contact your doctor immediately.

Blood pressure: If you have high blood pressure, discuss with your doctor how Lolo may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lolo, and whether any special monitoring is needed.

You may need to visit your doctor more frequently to have your blood pressure checked while using Lolo. Occasionally, high blood pressure may develop with the use of hormonal contraceptives. This may require stopping Lolo.

Breast cancer: Increasing age and a strong family history are the most significant risk factors for the development of breast cancer. Other established risk factors include Obesity, not having had children, and a late age at first full-term pregnancy. The identified groups of women that may be at increased risk of developing breast cancer before Menopause are women who have used birth control pills for more than 8 years or who started using them at an early age. For a few women, the use of birth control pills may accelerate the growth of an existing but undiagnosed breast cancer.

If you are taking birth control pills, learn how to perform a breast self-examination. Notify your doctor any time you detect a lump. A yearly clinical breast examination is also recommended because, if breast cancer develops, medications that contain estrogen may cause it to grow quickly.

Cervical cancer: Some studies have found an increase of cancer of the cervix in women who use hormonal contraceptives, although this finding may be related to factors other than the use of oral contraceptives.

Chronic infection with the human papillomavirus (HPV) is believed to be the most important risk factor for cervical cancer. Women who use combination oral contraceptives (COCs) for a long time may have a slightly higher chance of getting cervical cancer. This may not be caused by the contraceptive itself but may be related to sexual behavior and other factors.

Cholesterol: Blood cholesterol or triglyceride levels may increase while taking Lolo. People with cholesterol problems should discuss with their doctor how Lolo may affect their medical condition, and whether any special monitoring is needed.

Depression: Hormones, such as estrogen, have been known to cause mood swings and symptoms of depression. If you have had clinical depression in the past, you may be more likely to experience it again while taking Lolo. If you have depression or a history of depression, discuss with your doctor how Lolo may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lolo, and whether any special monitoring is needed.

If you experience symptoms of depression such as poor concentration, changes in weight, changes in sleep, decreased interest in activities, or notice them in a family member who is taking Lolo, contact your doctor as soon as possible.

Diabetes: Current low-dose birth control pills have very little effect on blood glucose control. If you have diabetes or a family history of diabetes, your doctor may want you to monitor your blood glucose closely to detect any worsening of blood sugar control after starting birth control pills.

If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Lolo may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lolo, and whether any special monitoring is needed.

Eyes: Women who are pregnant or who take birth control pills may experience fluid build-up in the cornea of the eye, which may cause visual disturbances and changes in tolerance to contact lenses, especially rigid contact lenses. Women who wear soft contact lenses usually do not experience difficulties. If you experience visual changes or alterations in tolerance to contact lenses, you may need to stop wearing the lenses temporarily or permanently.

Rarely, blood clots may form in the blood vessels in the eye, causing vision loss. Report any vision changes to your doctor immediately.

Fibroids: If you have fibroids (leiomyomata), your doctor should closely monitor your condition. If sudden enlargement, pain, or tenderness occurs, contact your doctor to see if you need to stop taking the medication.

Gallbladder disease: Women who use birth control pills have a greater risk of developing gallbladder disease. If you notice severe pain in the abdomen (stomach area), fever, or yellowing of skin or eyes (jaundice), contact your doctor immediately.

Headache: Birth control pills may cause migraine symptoms to develop or become worse. If you have a history of migraine headache, discuss with your doctor how Lolo may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lolo, and whether any special monitoring is needed.

Heart disease: Cigarette smoking increases the risk of serious heart disease and death. Taking birth control pills increases this risk, especially with increasing age. Studies show evidence that women who smoke and are over 35 years old should not use birth control pills.

Other women who have a high risk for heart disease include those with diabetes, high blood pressure, or abnormal cholesterol levels, or those with a family history of these conditions. Whether taking birth control pills increases this risk is unclear.

For low-risk, non-smoking women of any age, the benefits of birth control pill use outweigh the possible cardiovascular risks of low-dose pills.

Liver function: If you have reduced liver function or have had liver problems, discuss with your doctor how Lolo may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lolo, and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Lolo.

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Regular check-ups: You should have a yearly physical examination and follow-up visit with your doctor.

Return to fertility: After stopping birth control therapy, you should delay pregnancy until at least one normal menstrual cycle has occurred in order to date the pregnancy. An alternative birth control method (e.g., condoms) should be used during this time.

If you do not menstruate for 6 months or more after stopping birth control pills, notify your doctor.

Sexually transmitted infections: Birth control pills do not protect against sexually transmitted infections, including HIV/AIDS. For protection against these, use latex condoms.

Surgery: If you have surgery planned, make sure all the health care professionals involved in your care are aware that you are taking Lolo. Surgery may increase the risk of developing blood clots, particularly if you are not going to be able to get up and move around for a while.

Pregnancy: The hormones in birth control pills can affect the developing fetus if taken by a woman who is pregnant. If you become pregnant while taking Lolo, contact your doctor immediately.

Breast-feeding: The use of birth control pills while breast-feeding is not recommended. The hormonal components of the medication pass into breast milk and may reduce the quantity and quality of the breast milk. The long-term effects on the developing child are not known.

Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Yaz.

Blood clots: All hormonal contraceptives can increase the risk of developing blood clots. Some studies show that birth control pills containing drospirenone have a higher risk of blood clots than other birth control pills. Tell your doctor if you have a history of blood clots or are at risk of developing blood clots.

Tell your doctor if you are planning an upcoming surgery or if you will be immobilized or inactive for a prolonged period of time (i.e., through accident or illness), as there is an increased risk of blood clot formation when using combination hormonal contraceptives.

If you experience crushing chest pain or heaviness, pain in the calf, sudden shortness of breath, vision or speech changes, sudden severe headache, weakness or numbness in an arm or leg, or are coughing blood, get immediate medical attention, as these symptoms could indicate a possible blood clot.

Blood pressure: Yaz may increase blood pressure, increasing the risks of other heart problems. If you have high blood pressure, discuss with your doctor how Yaz may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Yaz, and whether any special monitoring is needed. You may need to visit your doctor more frequently to have your blood pressure checked while using Yaz.

Occasionally, high blood pressure may develop with the use of hormonal contraceptives. This may require stopping Yaz.

Cigarette smoking and heart disease: Cigarette smoking increases the risk of serious heart disease and death. Birth control pills also increase this risk, particularly as women get older. Women over 35 years of age who are heavy smokers (more than 15 cigarettes per day) should not use the birth control pill. All women are urged not to smoke while taking Yaz.

Other factors that increase your risk of heart disease include diabetes, high blood pressure, high cholesterol levels, or a family history of these conditions. It is unclear whether taking the birth control pill increases this risk.

For women who have a low risk of heart disease and do not smoke, the benefits of using low-dose birth control pills outweigh the possible risks of heart disease, regardless of age. These women may continue to use birth control pills up to the age of Menopause.

Depression: Yaz, like other birth control medications, may contribute to feelings of depression. If you have a history of depression or other emotional problems, discuss with your doctor how Yaz may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Yaz, and whether any special monitoring is needed. If you have a history of depression or other emotional problems you may be more likely to have a recurrence while taking oral birth control medications.

Diabetes: If you have diabetes, or have a family history of diabetes, discuss with your doctor how Yaz may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Yaz, and whether any special monitoring is needed. If you have diabetes, it may be necessary to test your blood sugar more often to detect any worsening of blood sugar control after starting birth control pills.

Electrolytes: Yaz contains the Progesterone drospirenone, which may increase potassium levels in women who are at high risk for this condition. Women with reduced kidney or liver function or inadequate production of adrenal hormones are at increased risk.

If you receive other medications that can increase your potassium you should have your potassium levels checked by your doctor when you first start Yaz. Some of these medications include potassium supplements, ACE inhibitors, angiotensin-II receptor antagonists (e.g., Candesartan, Losartan), some diuretics, Heparin, aldosterone antagonists (e.g., Spironolactone), and nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., Ibuprofen or Naproxen).

Eye disorders: Women who are taking birth control pills may experience fluid buildup in the cornea of the eye that may cause vision changes. This fluid buildup may also mean that your contact lenses may not fit as well as they used to, especially if you have hard contact lenses. Soft contact lenses usually do not cause problems. If your contact lenses feel uncomfortable, talk to your eye doctor.

Fibroid tumours: Yaz may worsen fibroid tumours (noncancerous growths in the uterus), causing sudden enlargement, pain, or tenderness. If you notice these effects, contact your doctor.

Gallbladder problems: The use of hormonal contraceptives increases the risk of gallbladder problems. If you experience symptoms of gallbladder problems such as severe stomach or back (between the shoulder blades) pain, nausea or vomiting, contact your doctor.

Kidney Disease: If you have kidney disease, discuss with your doctor how Yaz may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Yaz, and whether any special monitoring is needed. You may need to have regular blood tests while taking Yaz.

Liver disease: Although uncommon, the use of hormonal contraceptives has been associated with liver problems. See your doctor as soon as possible if you develop signs of liver problems such as yellow eyes or skin, abdominal pain, dark urine, pale stools, or itchy skin.

Migraine and headache: If you have migraines, discuss with your doctor how Yaz may affect your medical condition and whether any special monitoring is needed. Tell your doctor if you develop new types of headaches that are recurrent, persistent, or severe or if migraine headaches worsen.

Regular checkups: You should visit your doctor yearly for a physical examination and follow-up while you are taking Yaz.

Return to fertility: After stopping birth control therapy, you should delay pregnancy until at least one normal spontaneous menstrual cycle has occurred in order to date the pregnancy. An alternative birth control method should be used during this time. If you do not menstruate for 6 months or more after stopping birth control pills, notify your doctor.

Risk of cancer: The use of hormonal contraceptives may increase the risk of breast and cervical cancer in women before menopause (around age 50). If you have been using hormonal contraceptives for a long time (more than 8 years), started using them at an early age, or have a family history of cancer (mother or sister), you may be at an increased risk of developing cancer. Talk to your doctor about whether any special monitoring is needed.

If you are taking birth control pills, you should learn how to do a breast self-exam. Notify your doctor any time you detect a lump. In a few women, the use of birth control pills may speed up the growth of a breast cancer that has not yet been diagnosed. A yearly clinical breast examination is also recommended because, if breast cancer should develop, medications that contain estrogen may cause the cancer to grow quickly.

Sexually transmitted infections (STIs): Birth control pills do not protect against HIV/AIDS and other sexually transmitted infections (STIs; formerly known as sexually transmitted diseases or STDs). It is recommended that latex condoms be used in combination with Yaz to protect against these infections.

Pregnancy: Yaz should not be used during pregnancy. If you become pregnant while taking Yaz, or think that you may be pregnant, contact your doctor as soon as possible.

Breast-feeding: The hormones in Yaz pass into breast milk. Breast-feeding women should use another form of birth control until they are no longer breast-feeding. Talk to your doctor about your options.

Children: The safety and effectiveness of using Yaz have not been established for children under 14 years of age.