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Trileptal

Trileptal

(oxcarbazepine)

Trileptal (Oxcarbazepine) belongs to the group of medications known as antiepileptics. It is used to control Epilepsy in adults and children over 6 years of age.

Available form

Dosage

Tablet

150MG, 300MG, 600MG

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Trileptal information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The usual dose of Trileptal (Oxcarbazepine) for adults ranges from 300 mg to 600 mg twice a day, but some people may need up to 1,200 mg twice a day. The maximum dose is 1,200 mg twice a day.

For children over 6 years of age, the dose is based on body weight and is taken in divided doses, twice per day.

Trileptal (Oxcarbazepine) may be taken with or without food.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

If you are using the liquid form of Trileptal (Oxcarbazepine), shake the bottle of liquid well before measuring a dose. Use an oral syringe to measure each dose of the liquid, as it gives a more accurate measurement than household teaspoons.

It is important to take Trileptal (Oxcarbazepine) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Trileptal (Oxcarbazepine) at room temperature and keep it out of the reach of children. The liquid can be used for 7 weeks after opening the bottle (unless the expiry date on the package shows an earlier date), after which it should be discarded.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Trileptal (Oxcarbazepine). If you are concerned about side effects, discuss the risks and benefits of Trileptal (Oxcarbazepine) with your doctor.

The following side effects have been reported by at least 1% of people taking Trileptal (Oxcarbazepine). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

abdominal pain (mild)
Acne
anxiety
Constipation
difficulty concentrating
dizziness, drowsiness, or fatigue
hair loss
headache
nausea
problems with walking, speech, or coordination
trembling
skin rash (if there is no blistering or peeling and the rash is not covering a large area)
vomiting

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

abdominal pain (moderate to severe)
double vision or other vision changes
flu-like symptoms
nervousness, confusion, or feeling unusually emotional
signs of Anemia (low red blood cells; e.g., dizziness, pale skin, unusual tiredness or weakness, shortness of breath)
signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don’t stop bleeding)
signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
signs of infection (e.g., Fever or chills, severe Diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)
signs of liver problems (e.g., pale stools, dark urine, abdominal pain, itchy skin, yellow eyes or skin, or decreased appetite)
signs of low sodium in the blood (e.g., nausea, headache, weakness, sluggishness, confusion, or a general "ill" feeling)
signs of systemic Lupus erythematosus (e.g., red blotchy rash mainly on the face, with or without fatigue, fever, nausea)
symptoms of underactive Thyroid gland (e.g., dry skin, constipation, weight gain, fatigue, aches, pains and stiffness, intolerance to cold, depression, memory problems)
thoughts of suicide or self-harm

Stop taking the medication and seek immediate medical attention if any of the following occur:

signs of a serious allergic reaction (e.g., Hives, swelling of the face or throat, or difficulty breathing)
signs of bleeding in the stomach (e.g., bloody, black, or tarry stools, spitting up of blood, vomiting blood or material that looks like coffee grounds)
signs of a serious skin reaction (e.g., blistering or peeling of skin or a rash covering a large area of the body)
signs of a Stroke (e.g., sudden confusion, loss of speech, severe headache, dizziness, and weakness)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Trileptal (Oxcarbazepine).

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Trileptal (Oxcarbazepine).

Allergic reactions: About 25% to 30% of people who are allergic to the epilepsy medication Carbamazepine will also be allergic to Trileptal (Oxcarbazepine). If you have had an allergic reaction to carbamazepine, talk to your doctor before taking Trileptal (Oxcarbazepine).

Birth control: Trileptal (Oxcarbazepine), like other anticonvulsants, may reduce the effectiveness of birth control pills. Women taking Trileptal (Oxcarbazepine) should use an alternative, non-hormonal birth control method such as condoms. If you become pregnant while taking this medication, contact your doctor immediately.

Blood counts: This medication can decrease the number of neutrophils (a type of white blood cell that helps fight infection), red blood cells (which carry oxygen), and platelets (which help your blood to clot). Your doctor will do blood tests to monitor this. If you notice any signs of infection (e.g., fever, chills, or sore throat) or unusual bleeding or bruising, contact your doctor immediately.

Drowsiness/reduced alertness: Trileptal (Oxcarbazepine) may affect the mental or physical abilities needed to drive or operate machinery. Avoid driving, operating machinery, or performing other hazardous tasks until you have determined how Trileptal (Oxcarbazepine) affects you.

Heart conditions: The safety of using Trileptal (Oxcarbazepine) if you have a heart condition has not been determined. If you have a heart condition, discuss with your doctor how Trileptal (Oxcarbazepine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trileptal (Oxcarbazepine), and whether any special monitoring is needed.

Hypersensitivity syndrome: A Anaphylaxis (severe allergic reaction) called hypersensitivity syndrome has occurred for some people with the use of Trileptal (Oxcarbazepine). This reaction involves a number of organs in the body and may be fatal if not treated quickly. Stop taking the medication and get immediate medical attention if you have symptoms of a severe allergic reaction, including fever, swollen glands, yellowing of the skin or eyes, or flu-like symptoms with skin rash or blistering.

Kidney function: Kidney Disease or reduced kidney function may cause Trileptal (Oxcarbazepine) to build up in the body, causing side effects. If you have reduced kidney function or kidney disease, discuss with your doctor how Trileptal (Oxcarbazepine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trileptal (Oxcarbazepine), and whether any special monitoring is needed.

Liver function: Rarely, Trileptal (Oxcarbazepine) has been reported to cause inflammation of the liver and liver failure which has in cases, caused death. Trileptal (Oxcarbazepine) may also cause a decrease in liver function. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Low sodium: Trileptal (Oxcarbazepine) may cause low sodium levels. Get immediate medical attention if you notice the symptoms of very low sodium, such as nausea, headache, weakness, sluggishness, confusion, or a general feeling of being unwell.

Osteoporosis: Long term use of medications to treat seizures may cause weakened or brittle bones. Discuss with your doctor whether any special monitoring or supplements are needed.

Severe skin reactions: Trileptal (Oxcarbazepine) can cause serious skin reactions. If you have symptoms of a serious skin reaction, such as blistering or peeling of the skin, stop taking the medication and seek immediate medical attention.

Stopping medication: If this medication is stopped abruptly, the risk of seizures may increase. Talk to your doctor or pharmacist about how Trileptal (Oxcarbazepine) should be safely stopped.

Suicidal thoughts and behaviour: Some people taking anti-seizure medications may have suicidal thoughts or behaviour. If this happens to you or you notice this in a family member who is taking Trileptal (Oxcarbazepine), contact your doctor immediately. You should be closely monitored by your doctor for emotional and behaviour changes while taking Trileptal (Oxcarbazepine).

Thyroid problems: Some people taking Trileptal (Oxcarbazepine) develop changes in the function of their thyroid. Symptoms of these changes include feeling cold all the time, fatigue, weight loss, without a change in your diet or amount of exercise you get, or feeling emotional. Contact your doctor if you experience these symptoms.

Pregnancy: Trileptal (Oxcarbazepine) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Trileptal (Oxcarbazepine), contact your doctor immediately. Trileptal (Oxcarbazepine) can also contribute to folic acid deficiency. Talk to your doctor about folic acid supplements before and during pregnancy.

Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking Trileptal (Oxcarbazepine), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Trileptal (Oxcarbazepine) have not been established for children less than 6 years of age.

Seniors: Seniors may require lower doses of Trileptal (Oxcarbazepine). Do not change the way you are taking the medication without consulting your doctor.

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