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Banzel

Banzel

Rufinamide

Banzel (Rufinamide) belongs to the class of medications called antiepileptics (anti-seizure medications). It is used along with other seizure medications to help control the seizures associated with Lennox-Gastaut syndrome in adults and children 4 years of age and older.

Available form

Tablet

Dosage

100mg, 200mg, 400mg

Manufacturers

Eisai

Generic brand of

Rufinamide

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Banzel information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The recommended starting dose for people who weigh less than 30 kg is 100 mg taken twice a day. The recommended starting dose for people who weigh more than 30 kg is 200 mg taken twice a day.

Depending on your body's response to the medication and side effects, your doctor will gradually increase your daily dose until your seizures are controlled. The maximum daily dose is based on your body weight.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

In order to get the most benefit from each dose, take Banzel (Rufinamide) with food.

It is important to take Banzel (Rufinamide) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Banzel (Rufinamide) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Banzel (Rufinamide).

Abnormal heart rhythms: Banzel (Rufinamide) can cause changes to the normal rhythm of the heart, including an irregular heartbeat called QT shortening. QT shortening is a serious condition that can cause fainting and life-threatening heart rhythm problems.

If you are at risk for heart rhythm problems or are taking medications that cause QT shortening (e.g., Digoxin, Mexiletine, Phenytoin, magnesium sulfate), discuss with your doctor how Banzel (Rufinamide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Banzel (Rufinamide), and whether any special monitoring is needed. People who have or have had short QT syndrome or a family history of short QT syndrome should not take Banzel (Rufinamide).

Birth control: As with other anti-seizure medications, Banzel (Rufinamide) may reduce the effectiveness of oral contraceptives or other female hormonal treatments. It is advisable to use a non-hormonal form of birth control while you are taking Banzel (Rufinamide). Contact your doctor immediately if you experience changes in your menstrual pattern such as breakthrough bleeding while taking Banzel (Rufinamide).

Drowsiness/reduced alertness: People with uncontrolled Epilepsy should not drive or handle potentially dangerous machinery. Common side effects of Banzel (Rufinamide) include dizziness, problems with muscle coordination, drowsiness, double vision, and blurred vision. Do not undertake activities requiring mental alertness or physical coordination until you determine how Banzel (Rufinamide) affects you.

Galactose Intolerance/Glucose Malabsorption: Banzel (Rufinamide) contains lactose. If you have lactose intolerance or galactose malabsorption you should not take Banzel (Rufinamide).

Hypersensitivity (allergic) reactions: Rarely, Banzel (Rufinamide) can cause severe allergic reactions called "hypersensitivity syndrome," which may be life-threatening. This reaction involves a number of organs in the body and may be fatal if not treated quickly. Stop taking the medication and get immediate medical attention if you have symptoms of a Anaphylaxis (severe allergic reaction), including fever, swollen glands, yellowing of the skin or eyes, or flu-like symptoms with skin rash or blistering.

Stopping the medication: Suddenly stopping any antiepileptic medication may cause rebound seizures. In general, the medication should be stopped gradually, as directed by your doctor, to minimize this risk. Before stopping Banzel (Rufinamide), contact your doctor for guidance.

Suicidal thoughts or behaviour and depression: Like other antiepileptic medications, Banzel (Rufinamide) may cause thoughts of suicide or harming oneself. People with epilepsy may also experience depression.

If you experience agitation, restlessness, anxiety, aggressiveness, irritability, unusual changes in behaviour or mood, not feeling like yourself, or wanting to hurt yourself or others, contact your doctor immediately. If you notice these side effects in a family member who is taking Banzel (Rufinamide), contact their doctor immediately.

Vision problems: Banzel (Rufinamide) may cause vision changes or problems, including blurred vision, seeing double, dry eyes, and Eye Infections. Report any changes in your vision to your doctor as soon as possible.

Pregnancy: The effect of Banzel (Rufinamide) on a developing baby when taken during pregnancy is unclear. Banzel (Rufinamide) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Banzel (Rufinamide), contact your doctor immediately.

Do not stop taking the medication until you've consulted your doctor, since doing so can cause rebound seizures that may be harmful to the mother and unborn baby.

Breast-feeding: Banzel (Rufinamide) may pass into breast milk. If you are a breast-feeding mother and are taking Banzel (Rufinamide), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Banzel (Rufinamide) for children under 1 year of age have not been established.

Seniors: The use of Banzel (Rufinamide) by people over 65 years of age has not been well studied. Seniors are at increased risk of side effects of many medications and a lower than normal dose of Banzel (Rufinamide) may be appropriate.

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