Available in:Tablet
Dosage:500MG, 850MG
Manufacturer:Pharmascience
Available in:Injectable Pen, Long-Acting
Dosage:2MG/0.65ML
Manufacturer:Astrazeneca
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The recommended adult dose of metformin ranges from 500 mg 3 or 4 times a day to 850 mg 2 or 3 times a day. The maximum daily dose should not exceed 2,550 mg. Tablets should be taken with food whenever possible to reduce the risk of nausea and vomiting. Metformin may be used alone or with other medications that reduce blood sugar. To ensure that the medication is working well, monitor your blood glucose on a regular basis as directed by your doctor or diabetes educator.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Pms Metformin exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Pms Metformin at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
The usual adult dose of Bydureon (Exenatide) is 2 mg of extended release suspension, injected subcutaneously (under the skin) in the thigh, abdomen, or upper arm once a week.
Bydureon (Exenatide) extended-release is used with the guidance and supervision of a doctor. Your doctor or nurse will assist you in the preparation and injection of your first dose (or first few doses). Do not attempt to inject Bydureon (Exenatide) on your own until you completely understand how to inject a dose.
Bydureon (Exenatide) is provided in a pen injector that contains a glass cartridge with 2 compartments. One compartment contains the medication in a powder form, while the other compartment contains the diluent that, when mixed with the medication powder, creates a suspension that is injected. Read the user manual for instructions on how to properly use Bydureon (Exenatide). If you have questions about how to use Bydureon (Exenatide), contact your doctor or pharmacist.
Rotate the injection sites (arms, thighs, upper buttocks, or stomach) to minimize injection site skin irritation.
The diluent is clear and colourless and should not contain particles. After it has been mixed with the medication powder, the mixture will be white-to-off-white and cloudy. Inject the medication immediately after mixing the solution and powder.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important that Bydureon (Exenatide) be used exactly as prescribed by your doctor. If you miss a dose, and it is less than 3 days since the missed dose, inject it as soon as possible. If it is more than 3 days since the missed dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Bydureon (Exenatide) in the refrigerator, protect it from light, and keep it out of the reach of children. Do not allow it to freeze. If necessary, your pen may be stored at room temperature for up to 4 weeks.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Pms Metformin. If you are concerned about side effects, discuss the risks and benefits of Pms Metformin with your doctor.
The following side effects have been reported by at least 1% of people taking Pms Metformin. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Pms Metformin.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is used in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who uses Bydureon (Exenatide). If you are concerned about side effects, discuss the risks and benefits of Bydureon (Exenatide) with your doctor.
The following side effects have been reported by at least 1% of people taking Bydureon (Exenatide). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Bydureon (Exenatide).
500 mg
Each white, round, biconvex, coated tablet, imprinted "met" over "500" on the scored side and "P" logo on the other side, contains metformin HCl 500 mg. Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone PVK-90, and pregelatinized starch.
850 mg
Each white, capsule-shaped, biconvex, coated tablet, imprinted "P" logo on one side and "850" on the other side, contains metformin 850 mg. Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone PVK-90, and pregelatinized starch.
Each pen injector contains a dual chamber glass cartridge injector with a bypass channel and injection needle.
Do not take Pms Metformin if you:
Do not use Bydureon (Exenatide) if you:
There may be an interaction between metformin and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Pms Metformin. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
There may be an interaction between Bydureon (Exenatide) extended-release and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Bydureon (Exenatide). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Pms Metformin.
Alcohol intake: Anyone taking metformin should avoid excessive alcohol intake.
Blood sugar control: If you have fever, trauma, infection, or surgery, you may have a temporary loss of blood sugar control. At such times, your doctor may think it is necessary to stop metformin and temporarily inject insulin. Metformin may be started again after the problem is resolved.
Blood sugar monitoring: Monitor your blood sugar regularly at intervals as discussed with your doctor or diabetes educator.
Diabetes complications: The use of metformin (or any other medication used for diabetes) will not prevent the development of complications particular to diabetes mellitus (e.g., Kidney Disease, nerve disease, eye disease).
Diet: Metformin is a treatment to be taken in combination with a proper diet. Metformin is not a substitute for proper diet.
Dye or contrast agents: If you are going to have an X-ray procedure that uses dye or a contrast agent, you may need to stop taking Pms Metformin for a short time. Contact your doctor for instructions.
Kidney problems: Kidney disease or reduced kidney function causes Pms Metformin to build up in the body, causing side effects. If you have kidney problems, your doctor should closely monitor your condition while you are taking metformin, as it may affect kidney function.
Lactic acidosis: Lactic acidosis is a rare but serious problem that occurs due to metformin accumulation (i.e., the body doesn't get rid of it fast enough) during treatment. If you have severe kidney disease you are at higher risk of developing lactic acidosis. Since alcohol may increase the risk of lactic acidosis, do not drink a lot of alcohol over the short- or long-term while taking Pms Metformin. When it does occur (very rarely), it is fatal in 50% of cases. There have been no reports of lactic acidosis in Canada when metformin was used as directed. If you experience symptoms of lactic acidosis (e.g., weakness, tiredness, drowsiness, unusual muscle pain, trouble breathing, stomach pain with nausea, vomiting or diarrhea, feeling cold, dizziness, light-headedness, or slow or irregular heartbeat), stop taking Pms Metformin and get immediate medical attention.
Liver function: Decreased liver function has been linked to lactic acidosis. Pms Metformin is not recommended for people with severely reduced liver function. If you have moderately reduced liver function, discuss with your doctor how Pms Metformin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Metformin, and whether any special monitoring is needed.
Low blood sugar: Under usual circumstances, low blood sugar does not occur for people who take only metformin. Low blood sugar could occur when not enough food is eaten, especially when strenuous exercise is undertaken at the same time or when large amounts of alcohol have been consumed.
Reduced response: Over a period of time, you may become progressively less responsive to a particular treatment for diabetes because your diabetes worsens. If metformin fails to lower blood sugar to target levels, talk to your doctor. Your doctor may want to stop metformin or recommend another medication.
Surgery: Pms Metformin should be stopped temporarily for surgery (except for minor surgery where food and fluid intake is not restricted). You will be restarted on Pms Metformin once you are eating and drinking and your kidney function has been tested and is normal. Talk to your doctor for specific instructions.
Vitamin B12 levels: Pms Metformin may decrease vitamin B12 levels. Your doctor will monitor your B12 levels with blood tests while you are taking Pms Metformin.
Pregnancy: Pms Metformin should not be used during pregnancy. If you become pregnant while taking Pms Metformin, contact your doctor immediately.
Breast-feeding: Metformin is believed to pass into breast milk. Pms Metformin should not be used if you are breast-feeding.
Children: The safety and effectiveness of Pms Metformin have not been established for children.
Seniors: Kidney function often decreases with age. As a result, seniors may be more likely to experience side effects of Pms Metformin.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Bydureon (Exenatide).
Bleeding: Bydureon (Exenatide) may cause a reduced number of platelets in the blood, which can make it difficult to stop cuts from bleeding. If you notice any signs of bleeding, such as frequent nosebleeds, unexplained bruising, or black and tarry stools, notify your doctor as soon as possible.
Blood sugar control: Fever, infection, surgery, or trauma may cause a loss of blood sugar control and you may need to change to insulin temporarily, until you recover. Your doctor will recommend when this is needed.
If you regularly experience uncontrolled blood glucose levels, contact your doctor.
Diabetes identification: It is important to either wear a bracelet (or necklace) or carry a card indicating you have diabetes and are taking medication to manage your blood glucose levels.
Heart problems: Bydureon (Exenatide) extended-release may increase your heart rate and may affect how electrical impulses travel through the heart muscle. If you have heart disease (e.g., recent Heart Attack, Angina, heart failure) or an abnormal heart rhythm (e.g., heart block or fast heart rate), discuss with your doctor how Bydureon (Exenatide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Bydureon (Exenatide), and whether any special monitoring is needed.
If you experience dizziness, palpitations (a rapid, pounding, or irregular heartbeat), fainting, or seizures, get immediate medical attention.
Kidney problems: Bydureon (Exenatide) may cause kidney problems. Your doctor will monitor your kidney function with blood tests while you are using Bydureon (Exenatide). If you have had a kidney transplant or have reduced kidney function, discuss with your doctor how Bydureon (Exenatide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Bydureon (Exenatide), and whether any special monitoring is needed. If you are on dialysis or have severely reduced kidney function, you should not use Bydureon (Exenatide).
Low blood sugar (Hypoglycemia): Bydureon (Exenatide) may cause low blood sugar when it is used with sulfonylureas (e.g., glyburide, gliclazide) or insulin. If you are taking any of these types of medications, discuss with your doctor how Bydureon (Exenatide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Bydureon (Exenatide), and whether any special monitoring is needed.
If you experience symptoms of hypoglycemia such as a cold sweat, nervousness, or shakiness, fast heartbeat, headache, hunger, confusion, lightheadedness, weakness, and numbness or tingling of the tongue or lips, contact your doctor. Your doctor may need to adjust the dose of your medication(s).
Pancreatitis (inflammation of the pancreas): Bydureon (Exenatide) extended-release may cause pancreatitis that can be serious or life threatening. If you experience symptoms of pancreatitis such as severe and persistent abdominal pain that may move to your back and may be accompanied by vomiting, stop taking Bydureon (Exenatide) and contact your doctor or get immediate medical attention.
If you have previously had pancreatitis, gallstones, or alcohol use problems, discuss with your doctor how Bydureon (Exenatide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Bydureon (Exenatide), and whether any special monitoring is needed.
Stomach and intestinal problems: The safety and effectiveness of using Bydureon (Exenatide) have not been established for people who have inflammatory bowel disease (e.g., Crohn's Disease, Ulcerative Colitis) or slowed movement through the intestinal tract due to diabetes. If you have either of these conditions, you should not use Bydureon (Exenatide).
Thyroid cancer: It is not clear whether Bydureon (Exenatide) increases the risk of developing certain types of thyroid cancer. If you or a family member have ever had medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN 2), you should not use Bydureon (Exenatide).
If you experience possible symptoms of thyroid cancer, such as difficulty swallowing, hoarseness, trouble breathing or a mass in the neck, contact your doctor as soon as possible.
Pregnancy: Bydureon (Exenatide) should not be used during pregnancy unless the benefits outweigh the risks. If you are planning to become pregnant, Bydureon (Exenatide) should be stopped at least 3 months before becoming pregnant. If you become pregnant while using Bydureon (Exenatide), contact your doctor immediately.
Breast-feeding: It is not known if Bydureon (Exenatide) extended-release passes into breast milk. If you are a breast-feeding mother and are taking Bydureon (Exenatide), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Bydureon (Exenatide) have not been established for children and adolescents less than 18 years of age.
Seniors: If you are a senior, you may be more sensitive to the effects of Bydureon (Exenatide) and be more likely to experience side effects.
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Pharmacy Manager: Jasneet Dulai
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