Vivotif

The usual dose of Vivotif (Typhoid-vaccine-live) is one capsule taken every other day (e.g., day 1, 3, 5, and 7) for a total of 4 capsules. Take each capsule with at least 4 ounces (120 mL) of cool or lukewarm water (not warmer than 37°C or 98.6°F) approximately 1 hour before or 2 hours after a meal. The capsules should be swallowed whole (do not chew) as soon as possible after placing it in your mouth. All 4 capsules should be taken at least one week before being exposed to typhoid fever.

Although optimal booster doses have not been determined, it is recommended that a booster dose of 4 capsules taken on alternate days every 7 years be given if you have repeated or continued exposure to typhoid fever.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Vivotif (Typhoid-vaccine-live) exactly as prescribed by your doctor. If you miss a dose and it has been less than 24 to 28 hours from when you should have taken the dose, take the capsule as soon as you remember. Then skip a day and take the next dose and continue on the every-other-day dosing schedule. Do not take a double dose to make up for a missed one. If it has been longer than 48 hours from when you should have taken the capsule or you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Vivotif (Typhoid-vaccine-live) in the refrigerator at temperatures between 2°C and 8°C (35.6°F and 46.4°F). The vaccine may be left out of the refrigerator during a reasonable transit time home from the clinic or pharmacy. If the capsules are left outside of the refrigerator at room temperature 77°F (25°C) for up to 12 hours on a one-time only occasion, the product quality will not be affected and the capsules can still be taken.  Do not allow the capsules to freeze, protect them from light and moisture, and keep them out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.