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Reminyl ER

Reminyl ER

(galantamine)

Reminyl ER (Galantamine) belongs to the family of medications called cholinesterase inhibitors. It is used to treat symptoms of mild-to-moderate Alzheimer's Disease.

Available form

Dosage

24-Hour Release Capsule

8MG, 16MG, 24MG

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Reminyl ER information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The usual recommended starting dose of Reminyl ER (Galantamine) is 8 mg once daily. After at least 4 weeks of treatment, the dose may be increased to 16 mg once daily. After at least 4 more weeks of treatment, the dose may be increased further to 24 mg once daily.

Reminyl ER (Galantamine) capsules should be taken once daily in the morning with food. Swallow the capsules whole. Do not open, divide, crush, or chew them.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Reminyl ER (Galantamine) exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

People with Alzheimer's disease and their caregivers should be aware that if treatment has been interrupted for several days or longer, Reminyl ER (Galantamine) should be restarted at the lowest dose and then increased to the most current dose. If several doses are missed, do not restart Reminyl ER (Galantamine) on your own. It will be necessary to start at a lower dose and gradually increase to your previous dose. Consult your doctor if you miss several doses in a row.

Store Reminyl ER (Galantamine) at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Reminyl ER (Galantamine). If you are concerned about side effects, discuss the risks and benefits of Reminyl ER (Galantamine) with your doctor.

The following side effects have been reported by at least 1% of people taking Reminyl ER (Galantamine). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

abdominal pain
blurred vision
Diarrhea
Fever
flushing
general feeling of being unwell
headache
heartburn
leg cramps
lightheadedness
loss of appetite
muscle spasms
nausea
runny nose
sweating
tingling sensation in the hands or feet
tiredness
trouble sleeping
vomiting
weight loss

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

behavior changes (e.g., agitation, aggressiveness, confusion)
chest pain
difficulty holding urine
difficulty swallowing
falls
hallucinations (seeing or hearing things that are not there)
high blood pressure (e.g., dizziness, headache, vision changes, shortness of breath)
Low Blood Pressure (e.g., dizziness or fainting, especially when rising from a lying or sitting position)
ringing in the ears
signs of bleeding (e.g., bloody nose, blood in urine, coughing blood, cuts that don't stop bleeding)
signs of dehydration (e.g., decreased urine, dry skin, dry and sticky mouth, sleepiness, dizziness, headache, thirst, confusion)
signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
signs of low potassium levels in the blood (e.g., weakness, fatigue, muscle cramps, irregular heartbeat)
signs of urinary tract infection (e.g., blood in urine, pain or burning while urinating, need to urinate more often than normal)
slow or irregular heartbeat (less than 50 beats per minute)
tremor

Stop taking the medication and seek immediate medical attention if any of the following occur:

seizures
severe confusion
signs of bleeding in the stomach (e.g., bloody, black, or tarry stools; spitting up of blood; vomiting blood or material that looks like coffee grounds)
signs of a Heart Attack (e.g., chest pain or pressure, pain extending through shoulder and arm, nausea and vomiting, sweating)
signs of a severe skin reaction such as blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort
signs of Stroke (e.g., sudden or severe headache; sudden loss of coordination; vision changes; sudden slurring of speech; or unexplained weakness, numbness, or pain in arm or leg)
symptoms of a Anaphylaxis (severe allergic reaction) (e.g., itching or skin rash; shortness of breath; swelling of the face, lips, or tongue)
thoughts of self-harm or suicide

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Reminyl ER (Galantamine).

There may be an interaction between Reminyl ER (Galantamine) and any of the following:

other acetylcholinesterase inhibitors (e.g., Donepezil, Rivastigmine)
aclidinium
alpha-agonists (e.g., Clonidine, methyldopa)
amantadine
Amiodarone
antihistamines (e.g., Chlorpheniramine, Dimenhydrinate, Diphenhydramine)
antipsychotic medications (e.g., Haloperidol, Risperidone, Quetiapine)
atropine
azelastine
"azole" antifungals (e.g., fluconazole, ketoconazole, Voriconazole)
Benztropine
beta-blockers (e.g., Atenolol, Carvedilol, Metoprolol, Propranolol, Timolol)
Bupropion
Ceritinib
chloroquine
cholinergic agonists (e.g., Bethanechol, Pilocarpine)
corticosteroids (e.g., Hydrocortisone, Prednisone, Methylprednisolone)
Cyclobenzaprine
cyproheptadine
Digoxin
Diltiazem
Dipyridamole
Disopyramide
Dronedarone
Fesoterodine
Fingolimod
Flavoxate
glycopyrronium
Guanfacine
Hepatitis C antivirals (e.g., dasabuvir, ombitasvir, paritaprevir)
HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
ipratropium
Ivabradine
glycopyrrolate
macrolide antibiotics (e.g., azithromycin, clarithromycin, erythromycin)
Midodrine
monoamine oxidase inhibitors (M.O.S. Phenelzine, Moclobemide, Selegiline)
Octreotide
Oxybutynin
Pasireotide
quinidine
quinine
scopolamine
Solifenacin
SSRIs (e.g., Fluoxetine, Paroxetine, Sertraline)
succinylcholine-type neuromuscular blocking agents
tiotropium
Tizanidine
Tofacitinib
Tolterodine
Trazodone
tricyclic antidepressants (e.g., Amitriptyline, Desipramine, Nortriptyline)
umeclidinium
Verapamil

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

stop taking one of the medications,
change one of the medications to another,
change how you are taking one or both of the medications, or
leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Reminyl ER (Galantamine). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Reminyl ER (Galantamine).

Bladder problems: Reminyl ER (Galantamine) can make it more difficult to empty the bladder and may contribute to urinary tract problems. If you have bladder problems or a history of urinary tract problems, discuss with your doctor how Reminyl ER (Galantamine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Reminyl ER (Galantamine), and whether any special monitoring is needed.

Drowsiness/reduced alertness: Reminyl ER (Galantamine) may affect the mental or physical abilities needed to drive or operate machinery. Avoid driving, operating machinery, or performing other hazardous tasks until you have determined how Reminyl ER (Galantamine) affects you.

Gender: Women are more likely to experience side effects such as nausea and vomiting. This is also more likely to happen for women who are underweight.

Heart disease: Reminyl ER (Galantamine) can cause slowed heart rate, affecting people with Congestive Heart Failure (CHF) or Coronary Artery Disease (CAD). If you have a heart condition, including blood pressure problems, discuss with your doctor how Reminyl ER (Galantamine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Reminyl ER (Galantamine), and whether any special monitoring is needed.

Kidney function: If you have Kidney Disease or decreased kidney function, discuss with your doctor how Reminyl ER (Galantamine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Reminyl ER (Galantamine), and whether any special monitoring is needed. Reminyl ER (Galantamine) is not recommended for people with severely reduced kidney function.

Liver function: If you have liver disease or reduced liver function, discuss with your doctor how Reminyl ER (Galantamine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Reminyl ER (Galantamine), and whether any special monitoring is needed. Reminyl ER (Galantamine) is not recommended for people with severely reduced liver function.

Lung disease: Reminyl ER (Galantamine) can worsen the symptoms of breathing problems, such as Asthma or COPD (Chronic Obstructive Pulmonary Disease) (COPD) emphysema, and Bronchitis. If you have asthma, COPD, or any other breathing problem, discuss with your doctor how Reminyl ER (Galantamine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Reminyl ER (Galantamine), and whether any special monitoring is needed.

Seizures: An increase in seizures has been reported by people taking Reminyl ER (Galantamine). It is unclear whether this is because of the medication or the Alzheimer's disease. If you have or have had a seizure disorder, discuss with your doctor how Reminyl ER (Galantamine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Reminyl ER (Galantamine), and whether any special monitoring is needed.

Stomach ulcers: Reminyl ER (Galantamine) can cause an increase in the amount of acid produced by the stomach, increasing the risk for stomach ulcers. If you have or have had stomach problems, or take nonsteroidal anti-inflammatory (NSAIDs) medications, you are at increased risk of stomach problems with Reminyl ER (Galantamine). If you have any of these conditions, discuss with your doctor how Reminyl ER (Galantamine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Reminyl ER (Galantamine), and whether any special monitoring is needed.

Weight loss: People taking Reminyl ER (Galantamine) may experience significant weight loss. In some cases, this weight loss is unhealthy and may cause additional health problems. Let your doctor know about any weight loss that occurs.

Pregnancy: Reminyl ER (Galantamine) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Reminyl ER (Galantamine), contact your doctor immediately.

Breast-feeding: It is not known if Reminyl ER (Galantamine) passes into breast milk. If you are a breast-feeding mother and are taking Reminyl ER (Galantamine), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Reminyl ER (Galantamine) have not been established for children. Reminyl ER (Galantamine) is not intended to be used by children.

Seniors: People over 85 years of age may be at risk of more extreme weight loss when taking Reminyl ER (Galantamine).

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All material © 1996-2024 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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