Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Dom Indapamide.
Abnormal heart rhythms: Dom Indapamide can cause abnormal heart rhythms. Certain medications (e.g., Sotalol, quinidine, thioridazine, Chlorpromazine, Pimozide, moxifloxacin, Mefloquine, pentamidine, arsenic trioxide, probucol, Tacrolimus) can increase the risk of a type of abnormal heart rhythm called torsades de pointes and should be used with caution with indapamide.
If you are taking medication for abnormal heart rhythms, discuss with your doctor how Dom Indapamide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dom Indapamide, and whether any special monitoring is needed.
Allergy: Some people who are allergic to sulfonamides also experience allergic reactions to indapamide, as it has a sulfonamide component. Before you take indapamide, tell your doctor about any previous adverse reactions you have had to medications, especially sulfonamide (sulfa) antibiotics. Contact your doctor at once if you experience signs of an allergic reaction, such as skin rash, itching, difficulty breathing, or swelling of the face and throat.
Diabetes: Although indapamide has very little effect on blood sugar control, people with diabetes may need additional insulin to keep blood sugar levels steady. High blood sugar and sugar in the urine may occur for people who have risk factors for developing diabetes.
If you have diabetes, or are at risk for developing diabetes, discuss with your doctor how Dom Indapamide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dom Indapamide, and whether any special monitoring is needed.
Dizziness: Indapamide can cause severe dizziness, especially when rising from a sitting or lying position. This is more likely to occur when starting to take indapamide or increasing the dose being taken, particularly when other medications with similar side effects are being taken. If you are taking medications that can cause dizziness, rise slowly from sitting or lying down to reduce the possibility of severe dizziness or fainting.
Electrolytes: Changes in the blood levels of electrolytes such as potassium and magnesium become severe at doses above 2.5 mg per day. Do not take more than 2.5 mg per day.
Abnormally low blood potassium levels may occur at all doses causing weakness, cramps, and abnormal heart rhythms. The warning signs of electrolyte imbalance are:
- drowsiness
- dry mouth
- frequent urination
- Low Blood Pressure
- muscle fatigue
- muscle pains or cramps
- racing heartbeat
- restlessness
- stomach problems (e.g., nausea, vomiting)
- thirst
- tiredness
- weakness
Galactose intolerance: Indapamide medications are prepared with lactose. If you have lactose or galactose intolerance you should not take these medications.
Gout: Indapamide may increase the level of uric acid in the body. If you develop painful, warm and swollen joints contact your doctor as soon as possible. If you have a history of gout, discuss with your doctor how Dom Indapamide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dom Indapamide, and whether any special monitoring is needed.
Kidney function: Dom Indapamide is not helpful for people with severely reduced kidney function. If you have Kidney Disease or reduced kidney function, discuss with your doctor how Dom Indapamide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dom Indapamide, and whether any special monitoring is needed. If you experience a decrease in the amount of urine your body is producing, contact your doctor as soon as possible.
Liver function: If you have liver disease or reduced liver function, discuss with your doctor how Dom Indapamide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dom Indapamide, and whether any special monitoring is needed.
If you have severely reduced liver function you should not take indapamide because this increases the risk for developing liver-caused brain disease.
Sun sensitivity: Like other sulfonamide medications, indapamide may cause increased sensitivity to the effects of exposure to the sun. If you experience a severe sunburn-like reaction while taking indapamide, contact your doctor immediately. Regardless, you should take measures to protect yourself from the sun, such as use of an appropriate sunscreen and keeping exposed skin covered, while taking indapamide.
Systemic Lupus erythematosus: Dom Indapamide can worsen or activate the symptoms of lupus. If you experience swollen and painful joints, fever, fatigue, or rash on the nose and cheeks while taking Dom Indapamide, contact your doctor.
Pregnancy: In general, diuretics should not be used during pregnancy, due to the risk of reducing the growth of the fetus. Dom Indapamide should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Dom Indapamide, contact your doctor immediately.
Breast-feeding: Dom Indapamide passes into breast milk. If you are a breast-feeding mother and are taking indapamide, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of indapamide for use by children have not been established.
Seniors: Seniors may be at an increased risk of developing side effects to indapamide. Lower doses may be appropriate when using Dom Indapamide to treat high blood pressure for seniors.
