Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Pms Metformin. 

Alcohol intake: Anyone taking metformin should avoid excessive alcohol intake.

Blood sugar control: If you have fever, trauma, infection, or surgery, you may have a temporary loss of blood sugar control. At such times, your doctor may think it is necessary to stop metformin and temporarily inject insulin. Metformin may be started again after the problem is resolved.

Blood sugar monitoring: Monitor your blood sugar regularly at intervals as discussed with your doctor or diabetes educator.

Diabetes complications: The use of metformin (or any other medication used for diabetes) will not prevent the development of complications particular to diabetes mellitus (e.g., Kidney Disease, nerve disease, eye disease).

Diet: Metformin is a treatment to be taken in combination with a proper diet. Metformin is not a substitute for proper diet.

Dye or contrast agents: If you are going to have an X-ray procedure that uses dye or a contrast agent, you may need to stop taking Pms Metformin for a short time. Contact your doctor for instructions.

Kidney problems:  Kidney disease or reduced kidney function causes Pms Metformin to build up in the body, causing side effects. If you have kidney problems, your doctor should closely monitor your condition while you are taking metformin, as it may affect kidney function.

Lactic acidosis: Lactic acidosis is a rare but serious problem that occurs due to metformin accumulation (i.e., the body doesn't get rid of it fast enough) during treatment. If you have severe kidney disease you are at higher risk of developing lactic acidosis. Since alcohol may increase the risk of lactic acidosis, do not drink a lot of alcohol over the short- or long-term while taking Pms Metformin. When it does occur (very rarely), it is fatal in 50% of cases. There have been no reports of lactic acidosis in Canada when metformin was used as directed. If you experience symptoms of lactic acidosis (e.g., weakness, tiredness, drowsiness, unusual muscle pain, trouble breathing, stomach pain with nausea, vomiting or diarrhea, feeling cold, dizziness, light-headedness, or slow or irregular heartbeat), stop taking Pms Metformin and get immediate medical attention.

Liver function: Decreased liver function has been linked to lactic acidosis. Pms Metformin is not recommended for people with severely reduced liver function. If you have moderately reduced liver function, discuss with your doctor how Pms Metformin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Metformin, and whether any special monitoring is needed.

Low blood sugar: Under usual circumstances, low blood sugar does not occur for people who take only metformin. Low blood sugar could occur when not enough food is eaten, especially when strenuous exercise is undertaken at the same time or when large amounts of alcohol have been consumed.

Reduced response: Over a period of time, you may become progressively less responsive to a particular treatment for diabetes because your diabetes worsens. If metformin fails to lower blood sugar to target levels, talk to your doctor. Your doctor may want to stop metformin or recommend another medication.

Surgery: Pms Metformin should be stopped temporarily for surgery (except for minor surgery where food and fluid intake is not restricted). You will be restarted on Pms Metformin once you are eating and drinking and your kidney function has been tested and is normal. Talk to your doctor for specific instructions.

Vitamin B12 levels: Pms Metformin may decrease vitamin B12 levels. Your doctor will monitor your B12 levels with blood tests while you are taking Pms Metformin.

Pregnancy: Pms Metformin should not be used during pregnancy. If you become pregnant while taking Pms Metformin, contact your doctor immediately.

Breast-feeding: Metformin is believed to pass into breast milk. Pms Metformin should not be used if you are breast-feeding.

Children: The safety and effectiveness of Pms Metformin have not been established for children.

Seniors: Kidney function often decreases with age. As a result, seniors may be more likely to experience side effects of Pms Metformin.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Soliqua Solostar.

Allergic reactions: In rare cases, some people may develop an allergic reaction to Soliqua Solostar. Signs of an allergic reaction include a severe rash, Hives, swollen face or throat, or difficulty breathing. If these occur, contact your doctor immediately.

Blood glucose monitoring: It is important for anyone using insulin to monitor their blood glucose levels regularly, as recommended by their doctor or diabetes educator. It is especially important to test blood glucose more often when your insulin dose or schedule changes, or when you are ill or under stress. If blood tests consistently show high or low blood glucose levels, contact your doctor or diabetes educator.

Diabetes identification: It is important to either wear a bracelet (or necklace) or carry a card indicating you have diabetes and are taking medication to manage your blood glucose levels.

Heart problems: Insulin glargine-lixisenatide may increase heart rate and may affect how electrical impulses travel through the heart muscle, causing changes to heart rhythm. It can cause fluid to build up in the body and can contribute to heart failure. If you have heart disease (e.g., recent Heart Attack, Angina, heart failure) or an abnormal heart rhythm (e.g., heart block or fast heart rate), discuss with your doctor how Soliqua Solostar may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Soliqua Solostar, and whether any special monitoring is needed. Contact your doctor as soon as possible if you develop symptoms of heart problems such as shortness of breath, chest pain, rapid heartbeat, or swollen ankles.

Changes at injection site: Fatty tissue under the skin at the injection site may shrink or thicken if you inject yourself too often at the same site. To help avoid this effect, change the site with each injection. Talk to your doctor or diabetes educator if you notice your skin pitting or thickening at the injection site.

Intestinal problems: The safety and effectiveness of using Soliqua Solostar for people with inflammatory bowel disease (e.g., Crohn's Disease, Ulcerative Colitis) or who have slowed movement through the intestinal tract due to diabetes have not been established. If you have digestive system problems, discuss with your doctor how Soliqua Solostar may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Soliqua Solostar, and whether any special monitoring is needed.

Dehydration: Medications like lixisenatide can cause digestive system upset such as nausea, vomiting, and diarrhea. These effects can increase the risk of becoming dehydrated. If you experience digestive system side effects with insulin glargine - lixisenatide, make sure to drink enough fluids to replace what you are losing, to prevent dehydration. If you experience symptoms of dehydration, such as thirst, decreased urine or tear production, dizziness, or Headaches, contact your doctor.

Drowsiness/reduced alertness: Insulin glargine-lixisenatide may affect the mental or physical abilities needed to drive or operate machinery. Avoid driving, operating machinery, or performing other potentially hazardous tasks until you have determined how Soliqua Solostar affects you.

Kidney function: The safety and effectiveness of using Soliqua Solostar for people with reduced kidney function has not been studied. Ensure that you are drinking enough water to prevent dehydration if you experience nausea or vomiting with Soliqua Solostar. If you have reduced kidney function or Kidney Disease, discuss with your doctor how Soliqua Solostar may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Soliqua Solostar, and whether any special monitoring is needed.

Liver function: People with decreased liver function or liver disease may require lower doses of insulin to control blood glucose. If you have reduced liver function or liver disease, discuss with your doctor how Soliqua Solostar may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Soliqua Solostar, and whether any special monitoring is needed.

Low blood glucose (hypoglycemia): People who use insulin are more at risk of experiencing hypoglycemia (low blood sugar). Symptoms of mild-to-moderate hypoglycemia may occur suddenly and can include cold sweat, nervousness or shakiness, fast heartbeat, headache, hunger, confusion, lightheadedness, weakness, and numbness or tingling (tongue, lips, or fingers).

Mild-to-moderate hypoglycemia may be treated by eating foods or drinks that contain sugar. You should always carry a quick source of sugar, such as hard candies, glucose tablets, juice, or regular soft drinks (not diet soft drinks). If you experience symptoms of hypoglycemia, eat one of these sources of sugar and then rest. If you feel symptoms of hypoglycemia coming on, don't take insulin.

Signs of severe hypoglycemia can include disorientation, loss of consciousness, and seizures. People who are unable to take sugar by mouth or who are unconscious may require an injection of Glucagon or treatment with intravenous (into the vein) glucose.

Pancreatitis (inflammation of the pancreas): Pancreatitis has been associated with the medication lixisenatide. If you experience symptoms of pancreatitis such as severe and persistent abdominal pain that may move to the back with or without vomiting, contact your doctor immediately. If you have previously had pancreatitis, discuss with your doctor how Soliqua Solostar may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Soliqua Solostar, and whether any special monitoring is needed.

Risk of thyroid cancer: In rare cases, people have developed thyroid cancer while using medications similar to lixisenatide. People with a personal or family history of thyroid cancer or people who have multiple endocrine neoplastic syndrome type 2 (a disease where people have tumors in more than one gland in their body) should not use Soliqua Solostar.

Pregnancy: Soliqua Solostar should not be used during pregnancy. If you become pregnant while taking Soliqua Solostar, contact your doctor immediately.

Breast-feeding: It is not known if insulin glargine-lixisenatide passes into breast milk. If you are breast-feeding and are taking Soliqua Solostar, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Soliqua Solostar have not been established for children.

Seniors: People over the age of 65 are more likely to experience side effects of taking insulin glargine-lixisenatide. Doses for seniors may need to be lower and increased more slowly than for other adults.