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Prazosin

Prazosin

Prazosin (Prazosin) belongs to the family of medications called antihypertensives, specifically the group known as alpha 1-blockers. It is used to treat mild-to-moderate high blood pressure.

Available form

Tablet, Capsule

Dosage

0.5mg, 1mg, 2mg, 5mg

Manufacturers

Apotex, Erfa, Teva

Branded drugs

Minipress

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Prazosin information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

Directions of use

The recommended adult dose of Prazosin (Prazosin) starts with 0.5 mg with the evening meal and is increased gradually until the desired effect is achieved. The maximum dose is 20 mg daily, taken in 2 or 3 divided doses with food. Prazosin (Prazosin) may be used alone or in combination with other medications for lowering blood pressure.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Prazosin (Prazosin) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Prazosin (Prazosin) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Prazosin (Prazosin). If you are concerned about side effects, discuss the risks and benefits of Prazosin (Prazosin) with your doctor.

The following side effects have been reported by at least 1% of people taking Prazosin (Prazosin). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

abdominal discomfort
Constipation
Diarrhea
dizziness or lightheadedness, especially when rising from a lying or sitting position
drowsiness
Dry Mouth
headache
lack of energy
nausea
unusual tiredness or weakness
vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

blurred vision
chest pain
fainting (sudden)
frequent urge to urinate
loss of bladder control
pounding or irregular heartbeat
signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
shortness of breath
swelling of feet or lower legs

Stop taking the medication and seek immediate medical attention if any of the following occur:

long-lasting (greater than 4 hours) and painful erection of the penis
signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, Fever, chills, rapid heartbeat, swollen abdomen)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Prazosin (Prazosin).

There may be an interaction between Prazosin (Prazosin) and any of the following:

Aldesleukin
Aliskiren
alpha agonists (e.g., Clonidine, methyldopa)
alpha/beta agonists (e.g., Epinephrine, norepinephrine)
alpha blockers (e.g., Alfuzosin, Doxazosin, Silodosin, Tamsulosin)
amifostine
amphetamines (e.g., Dextroamphetamine, Lisdexamfetamine)
angiotensin converting enzyme inhibitors (ACEIs; Captopril, Enalapril, Ramipril)
angiotensin receptor blockers (ARBs; e.g., Candesartan, Irbesartan, Losartan)
second generation anti-psychotics (e.g., Clozapine, Olanzapine, Quetiapine, Risperidone)
barbiturates (e.g., butalbital, pentobarbital Phenobarbital)
beta-adrenergic blockers (e.g., Atenolol, Propranolol, Sotalol)
brimonidine
calcium channel blockers (e.g., Amlodipine, Diltiazem, Nifedipine, Verapamil)
decongestants (e.g., phenylephrine, Pseudoephedrine)
diuretics (water pills; e.g., Furosemide, Hydrochlorothiazide, triamterene)
Duloxetine
Guanfacine
levodopa
Methylphenidate
Minoxidil
nitrates (e.g., Nitroglycerin, isosorbide dinitrate, isosorbide mononitrate)
Obinutuzumab
Pentoxifylline
phosphodiesterase 5 inhibitors (e.g., Sildenafil, Tadalafil, Vardenafil)
quinine
Yohimbine

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

stop taking one of the medications,
change one of the medications to another,
change how you are taking one or both of the medications, or
leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Prazosin (Prazosin). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Prazosin (Prazosin).

Drowsiness/reduced alertness: Prazosin (Prazosin) can cause severe dizziness and lightheadedness. Avoid driving or operating dangerous machinery until you determine how Prazosin (Prazosin) affects you. Speak with your doctor if you experience severe dizziness or lightheadedness while taking Prazosin (Prazosin).

Kidney problems: If you have reduced kidney function, discuss with your doctor how Prazosin (Prazosin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Prazosin (Prazosin), and whether any special monitoring is needed.

Orthostatic hypotension: Prazosin (Prazosin) has been known to cause severe dizziness and even loss of consciousness for people moving from a sitting or lying position to a standing position. This is known as orthostatic hypotension. It happens most commonly if the person is already taking another blood pressure-lowering medication, has just started treatment with Prazosin (Prazosin), or starts treatment with Prazosin (Prazosin) at a higher dose.

To help prevent this, get up slowly from a sitting or lying position. Your doctor will also recommend slowly increasing the dose of Prazosin (Prazosin).

Pregnancy: Prazosin (Prazosin) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Prazosin (Prazosin), contact your doctor immediately.

Breast-feeding: Prazosin (Prazosin) passes into breast milk. If you are a breast-feeding mother and are taking Prazosin (Prazosin), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Prazosin (Prazosin) have not been established for children under 12 years of age.

Seniors: Seniors may be more at risk of side effects such as dizziness and Low Blood Pressure.

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All material © 1996-2025 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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