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Metoclopramide

Metoclopramide

(metoclopramide)

Metoclopramide belongs to the classes of medications called antiemetics and prokinetics. It is used to improve stomach emptying after surgery or other procedures.

Available form

Dosage

Injectable

5MG/ML

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Metoclopramide information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The recommended adult dose of metoclopramide for symptoms resulting from delayed stomach emptying ranges from 5 mg to 10 mg 3 or 4 times daily before meals. The recommended dose for children (aged 5 to 14 years) is 2.5 mg to 5 mg 3 times daily before meals. The injectable form of metoclopramide is most often used for the prevention of nausea and vomiting caused by chemotherapy. It is usually given by a health care professional in a hospital. The maximum daily dose for both adults and children is 0.5 mg/kg of body weight.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Metoclopramide exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Metoclopramide at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Metoclopramide. If you are concerned about side effects, discuss the risks and benefits of Metoclopramide with your doctor.

The following side effects have been reported by at least 1% of people taking Metoclopramide. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

Diarrhea (with high doses)
difficulty sleeping
dizziness
drowsiness
fatigue
headache
restlessness

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

difficulty speaking or swallowing
dizziness or fainting
fast or irregular heartbeat
Fever
general feeling of tiredness or weakness
headache (severe or continuing)
inability to move eyes
increase in blood pressure
lip smacking or puckering
loss of balance control
mask-like face
muscle spasms of face, neck, and back
puffing of cheeks
rapid or worm-like movements of tongue
shuffling walk
signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
sore throat
stiffness of arms or legs
tic-like or twitching movements
trembling and shaking of hands and fingers
twisting movements of body
uncontrolled chewing movements
uncontrolled movements of arms and legs
unusual eye movements
weakness of arms and legs

Stop taking the medication and seek immediate medical attention if any of the following occur:

signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, swelling of the face and throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Metoclopramide.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Metoclopramide.

Drowsiness/reduced alertness: Metoclopramide may cause drowsiness and increase the drowsiness caused by alcohol and other drugs. Avoid driving and doing other potentially hazardous activities until you have determined the effect Metoclopramide has on you.

Medical conditions: If you have Epilepsy, Parkinson's Disease, or Kidney Disease, discuss with your doctor how Metoclopramide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Metoclopramide, and whether any special monitoring is needed.

Tardive dyskinesia (TD): Metoclopramide may cause tardive dyskinesia (TD) to develop. TD is a potentially irreversible syndrome of involuntary, repetitive movements of the face and tongue muscles. Although TD appears most commonly in seniors, especially women, it is impossible to predict who will develop TD. The risk of developing TD increases with higher doses and long-term treatment. If you experience muscle twitching or abnormal movements of the face or tongue, contact your doctor as soon as possible.

Pregnancy: Metoclopramide should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Metoclopramide, contact your doctor immediately.

Breast-feeding: Metoclopramide passes into breast milk. If you are a breast-feeding mother and are taking metoclopramide, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: Metoclopramide should not be used in children less than one year of age. It should only be used in children over one year of age when the benefits of treatment outweigh the risks of side effects. Children may be more at risk of experiencing abnormal involuntary movements such as tremors and abnormal twitching movements, even at recommended dosages.

Seniors: Seniors appear to have a higher risk of side effects with long-term treatment of metoclopramide.

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