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Lescol Xl

Lescol Xl

Fluvastatin

Lescol XL (Fluvastatin) belongs to the family of medications known as cholesterol-lowering drugs. It is used in addition to diet and exercise to treat adults with High Cholesterol levels and children aged 10 years and older who have been diagnosed with heterozygous familial hypercholesterolemia.

Available form

Capsule

Dosage

20mg, 40mg

Manufacturers

Novartis Pharmaceuticals, Sandoz

Generic brand of

Fluvastatin

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Lescol Xl information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

Before starting Lescol XL (Fluvastatin), you should be following a cholesterol-lowering diet. If appropriate, your health care professionals will discuss an individualized program of weight control and physical exercise with you.

The starting dose of Lescol XL (Fluvastatin) for adults depends on the LDL-C level and goal of treatment.

The recommended adult dose of Lescol XL (Fluvastatin) ranges from 20 mg to 80 mg daily. Up to 60 mg daily can be taken as one dose in the evening or at bedtime. The 80 mg daily dose can be taken as one 40 mg capsule twice daily, with or after meals, or as one 80 mg extended-release capsule taken once daily. (The extended-release capsule may be taken at any time of day, but should be taken at the same time every day.)

The recommended dose of Lescol XL (Fluvastatin) to prevent heart attack after angioplasty is 40 mg taken twice a day.

Children 10 years of age and older should be following a cholesterol-lowering diet for 6 months before starting Lescol XL (Fluvastatin). The recommended starting dose for children and adolescents is 20 mg taken once daily. If necessary, the dose may be gradually increased to 80 mg daily.

Lescol XL (Fluvastatin) may be taken with or without food, but it should be taken consistently with regard to food (always with food or always without food).

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

For best results in lowering cholesterol, it is important that you closely follow the diet suggested by your doctor. Lescol XL (Fluvastatin) may not change how you feel, but it may help to prevent possible health problems in the future.

It is important to take Lescol XL (Fluvastatin) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Lescol XL (Fluvastatin) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Lescol XL (Fluvastatin). If you are concerned about side effects, discuss the risks and benefits of Lescol XL (Fluvastatin) with your doctor.

The following side effects have been reported by at least 1% of people taking Lescol XL (Fluvastatin). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

abdominal pain
Constipation
decreased sexual ability
Diarrhea
difficulty sleeping
dizziness
headache
heartburn
nausea
nightmares

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

confusion
memory problems
signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)
symptoms of liver damage such as:

abdominal pain
clay-coloured stools
dark urine
itching
loss of appetite
nausea and vomiting
yellow skin or eyes

symptoms of muscle damage (muscle pain, tenderness or weakness, brown or discoloured urine – especially if you also have a Fever or a general feeling of being unwell)
symptoms of severe abdominal pain (inflamed pancreas)

Stop taking the medication and seek immediate medical attention if any of the following occur:

severe skin rash, including skin blistering and peeling (possibly with headache, fever, coughing, or aching before the rash begins)
symptoms of a serious allergic reaction (such as swelling of the face or throat, Hives, or difficulty breathing)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Lescol XL (Fluvastatin).

Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Lescol XL (Fluvastatin).

Alcohol: People who drink large quantities of alcohol should be closely monitored by their doctor while they are taking Lescol XL (Fluvastatin).

Diabetes: Lescol XL (Fluvastatin), like other medications in this class, may cause a loss of blood glucose control, and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Lescol XL (Fluvastatin).

If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Lescol XL (Fluvastatin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lescol XL (Fluvastatin), and whether any special monitoring is needed.

If you experience symptoms of increased blood sugar, such as increased thirst, need to urinate more often or a fruity odour to your breath, contact your doctor as soon as possible.

Kidney Disease: There is little experience with the use of Lescol XL (Fluvastatin) by people with severe kidney disease. It is currently not recommended for people with severely decreased kidney function.

Liver effects: Liver disease or reduced liver function may cause Lescol XL (Fluvastatin) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Lescol XL (Fluvastatin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lescol XL (Fluvastatin), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Lescol XL (Fluvastatin).

Lescol XL (Fluvastatin) may also cause liver damage or liver failure. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Muscle effects: In rare cases, serious muscle damage has been associated with the use of statin medications (i.e., cholesterol-lowering drugs whose names end in "statin," such as Atorvastatin, Lescol XL (Fluvastatin), Lovastatin, Pravastatin, Rosuvastatin, or Simvastatin), especially at higher doses. Before taking Lescol XL (Fluvastatin), tell your doctor or pharmacist if you:

are over the age of 70
are frail
are taking other cholesterol-lowering medications such as fibrates (Gemfibrozil, Fenofibrate) or Niacin
are taking other medications, including prescription, non-prescription, and natural health products, as drug interactions are possible
do large amounts of physical exercise
have very Low Blood Pressure
have a severe metabolic, endocrine, or electrolyte disorders
have sepsis (blood infection)
have uncontrolled Epilepsy
have a family history of muscular disorders
have diabetes
have had any past problems with the muscles (pain, tenderness) after taking a statin
have kidney or liver problems
have Thyroid problems
have undergone surgery or other tissue injury
regularly drink 3 or more alcoholic drinks daily

Report any unexplained muscle pain, tenderness, weakness, or cramps, or any brown or discoloured urine to your doctor immediately, particularly if you are also experiencing malaise (a general feeling of being unwell) or fever.

Pregnancy: Lescol XL (Fluvastatin) should not be taken by pregnant women. If you become pregnant while taking Lescol XL (Fluvastatin), stop taking the medication immediately and contact your doctor.

Breast-feeding: It is not known if Lescol XL (Fluvastatin) passes into breast milk. If you are a breast-feeding mother and are taking Lescol XL (Fluvastatin), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of Lescol XL (Fluvastatin) have not been established for children less than 10 years old.

Seniors: If you are older than 70 years of age, your doctor will likely monitor you closely for muscle-related side effects.

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