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Herceptin

Herceptin

(trastuzumab)

Herceptin (Trastuzumab) belongs to the group of cancer-fighting medications known as antineoplastics, and in particular to the family of medications known as monoclonal antibodies. It is used in addition to other therapies to treat early stage Breast Cancer and metastatic (cancer that has spread) breast cancer that produce a substance known as HER2 protein.

Available form

Dosage

Injectable Powder

440MG

Buy Herceptin Full drug details

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Herceptin information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The recommended dose and dosing schedule of Herceptin (Trastuzumab) varies according to body size and the type of cancer. It is injected into a vein through a specially prepared site on your skin over 90 minutes. The medication may be injected over 30 minutes if previous doses were tolerated well.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are receiving Herceptin (Trastuzumab) without consulting your doctor.

Very careful handling of Herceptin (Trastuzumab) is required. It is always given under the supervision of a doctor in a hospital or similar setting with access to sterile equipment for preparation.

Herceptin (Trastuzumab) can cause a number of side effects. It may cause nausea and vomiting, but medications can be given to control this. Your doctor, nurse, or pharmacist can advise you on how to reduce the effects of nausea and vomiting. Keep track of any side effects and report them to your doctor as suggested in the section, "What side effects are possible with Herceptin (Trastuzumab)?"

It is important Herceptin (Trastuzumab) be given exactly as recommended by your doctor. If you miss an appointment to receive Herceptin (Trastuzumab), contact your doctor as soon as possible to reschedule your appointment.

Herceptin (Trastuzumab) is stored in the refrigerator.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who receives Herceptin (Trastuzumab). If you are concerned about side effects, discuss the risks and benefits of Herceptin (Trastuzumab) with your doctor.

The following side effects have been reported by at least 1% of people receiving Herceptin (Trastuzumab). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

appetite loss
changes in nails
Constipation
cough
fatigue
Fever and chills
headache
mild Diarrhea
nausea
pain (e.g., muscle and joint pain)
vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

diarrhea (more than 4 extra bowel movements a day or any at night)
fast heartbeat
itching
signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don’t stop bleeding)
symptoms of an infusion reaction (e.g., itching, wheezing, dizziness, fast heart rate)
symptoms of Anemia (e.g., shortness of breath, tiredness, fast heart rate)
symptoms of heart problems (e.g., swelling of feet or lower legs, shortness of breath)
symptoms of infection (e.g., fever or chills, sore throat, cough, redness or swelling, painful urination)
symptoms of kidney problems (e.g., decreased urine production; drowsiness; shortness of breath; fatigue; swelling of the legs, ankles, or feet)
symptoms of lung problems (e.g., shortness of breath, wheezing, or coughing)
trouble swallowing

Seek immediate medical attention if any of the following occur:

chest pain
shortness of breath
symptoms of an allergic reaction (e.g., Hives; dizziness; fast heart rate; difficulty breathing; swelling of the lips, tongue, or throat)
wheezing

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Herceptin (Trastuzumab).

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Herceptin (Trastuzumab).

Allergic reactions: Herceptin (Trastuzumab) may cause an allergic reaction (e.g., dizziness; hives; fast heart rate; swelling of the lips, tongue, or throat). If you experience these symptoms, tell your doctor immediately.

Heart disease: Herceptin (Trastuzumab) can cause heart problems such as heart failure. People with heart disease are more at risk for these problems. Your doctor will perform tests at regular intervals to monitor for any changes in your heart function. If you experience symptoms of heart function changes such as shortness of breath, worsening cough, difficulty breathing at night, swelling of the feet or hands, contact your doctor immediately.

Infection: As well as killing cancer cells, Herceptin (Trastuzumab) can reduce the number of cells that fight infection in the body (white blood cells). Avoid contact with people who have contagious infections and tell your doctor if you begin to notice signs of an infection, such as fever or chills.

Infusion reactions: Herceptin (Trastuzumab) can cause reactions that are related to the infusion. Symptoms of a reaction include itching, dizziness, wheezing, fast heart rate, difficulty breathing, and a dramatic drop in blood pressure. The reaction does not usually last very long, but may need to be treated as it can cause death if it is severe. The reaction usually occurs during or shortly after receiving the medication, but can also be delayed. If you experience symptoms of an infusion reaction, let your nurse or doctor know immediately or get immediate medical attention.

Lung problems: Herceptin (Trastuzumab) can cause lung problems, especially for people with lung disease or Lung Cancer, or who have received or are receiving other anticancer medications or radiation therapy. Let your doctor know immediately if you begin to experience shortness of breath or persistent cough.

Preservative: The intravenous form of Herceptin (Trastuzumab) contains benzyl alcohol, which acts as a preservative. Inform a member of your health care team if you have had a previous reaction to benzyl alcohol.

Pregnancy: Herceptin (Trastuzumab) can cause harm to the fetus if used during pregnancy. Women who could become pregnant should use effective contraception while receiving Herceptin (Trastuzumab) and for 7 months after stopping it. If you become pregnant while taking Herceptin (Trastuzumab), contact your doctor immediately.

Breast-feeding: It is not known if Herceptin (Trastuzumab) passes into breast milk. If you are a breast-feeding mother and are receiving Herceptin (Trastuzumab), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Herceptin (Trastuzumab) have not been established for children.

Seniors: Seniors may be more at risk for experiencing certain side effects from Herceptin (Trastuzumab).

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