Available in:Tablet
Dosage:500MG, 850MG
Manufacturer:Pharmascience
Available in:Autoinjector
Dosage:0.75MG, 1.5MG
Manufacturer:Eli Lilly
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The recommended adult dose of metformin ranges from 500 mg 3 or 4 times a day to 850 mg 2 or 3 times a day. The maximum daily dose should not exceed 2,550 mg. Tablets should be taken with food whenever possible to reduce the risk of nausea and vomiting. Metformin may be used alone or with other medications that reduce blood sugar. To ensure that the medication is working well, monitor your blood glucose on a regular basis as directed by your doctor or diabetes educator.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Pms Metformin exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Pms Metformin at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
The recommended adult starting dose of Trulicity (Dulaglutide) is 0.75 mg, injected subcutaneously (under the skin), once a week. It may be injected at any time of the day, without regard to meals. If necessary, your doctor may increase the dose to a maximum of 1.5 mg once weekly. Do not change your dose unless your doctor has told you to do so. Your doctor or diabetes educator will show you how to inject Trulicity (Dulaglutide).
If you are also using insulin, each medication should be injected separately. Trulicity (Dulaglutide) should be clear and colourless. Do not use Trulicity (Dulaglutide) if you notice anything unusual in the appearance of the solution, such as cloudiness, discolouration, or clumping.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Trulicity (Dulaglutide) exactly as prescribed by your doctor. If you miss a dose, inject it as soon as possible and continue with your regular schedule. If it is less than 3 days until your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Trulicity (Dulaglutide) in the refrigerator; do not allow it to freeze. Protect it from direct heat and light. Keep this and all medication out of the reach of children. These single-use prefilled pens and syringes may be stored at room temperature for up to 14 days.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Pms Metformin. If you are concerned about side effects, discuss the risks and benefits of Pms Metformin with your doctor.
The following side effects have been reported by at least 1% of people taking Pms Metformin. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Pms Metformin.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Trulicity (Dulaglutide). If you are concerned about side effects, discuss the risks and benefits of Trulicity (Dulaglutide) with your doctor.
The following side effects have been reported by at least 1% of people taking Trulicity (Dulaglutide). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Trulicity (Dulaglutide).
500 mg
Each white, round, biconvex, coated tablet, imprinted "met" over "500" on the scored side and "P" logo on the other side, contains metformin HCl 500 mg. Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone PVK-90, and pregelatinized starch.
850 mg
Each white, capsule-shaped, biconvex, coated tablet, imprinted "P" logo on one side and "850" on the other side, contains metformin 850 mg. Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone PVK-90, and pregelatinized starch.
0.75 mg/0.5 mL
Each single-use prefilled pen or prefilled syringe contains 0.75 mg of Trulicity (Dulaglutide) per 0.5 mL of solution. Nonmedicinal ingredients: trisodium citrate dehydrate, citric acid anhydrous, mannitol, and polysorbate 80 in water for injection.
1.5 mg/0.5 mL
Each single-use prefilled pen or prefilled syringe contains 1.5 mg of Trulicity (Dulaglutide) per 0.5 mL of solution. Nonmedicinal ingredients: trisodium citrate dehydrate, citric acid anhydrous, mannitol, and polysorbate 80 in water for injection.
Do not take Pms Metformin if you:
Do not take Trulicity (Dulaglutide) if you:
There may be an interaction between metformin and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Pms Metformin. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
There may be an interaction between Trulicity (Dulaglutide) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Trulicity (Dulaglutide). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Pms Metformin.
Alcohol intake: Anyone taking metformin should avoid excessive alcohol intake.
Blood sugar control: If you have fever, trauma, infection, or surgery, you may have a temporary loss of blood sugar control. At such times, your doctor may think it is necessary to stop metformin and temporarily inject insulin. Metformin may be started again after the problem is resolved.
Blood sugar monitoring: Monitor your blood sugar regularly at intervals as discussed with your doctor or diabetes educator.
Diabetes complications: The use of metformin (or any other medication used for diabetes) will not prevent the development of complications particular to diabetes mellitus (e.g., Kidney Disease, nerve disease, eye disease).
Diet: Metformin is a treatment to be taken in combination with a proper diet. Metformin is not a substitute for proper diet.
Dye or contrast agents: If you are going to have an X-ray procedure that uses dye or a contrast agent, you may need to stop taking Pms Metformin for a short time. Contact your doctor for instructions.
Kidney problems: Kidney disease or reduced kidney function causes Pms Metformin to build up in the body, causing side effects. If you have kidney problems, your doctor should closely monitor your condition while you are taking metformin, as it may affect kidney function.
Lactic acidosis: Lactic acidosis is a rare but serious problem that occurs due to metformin accumulation (i.e., the body doesn't get rid of it fast enough) during treatment. If you have severe kidney disease you are at higher risk of developing lactic acidosis. Since alcohol may increase the risk of lactic acidosis, do not drink a lot of alcohol over the short- or long-term while taking Pms Metformin. When it does occur (very rarely), it is fatal in 50% of cases. There have been no reports of lactic acidosis in Canada when metformin was used as directed. If you experience symptoms of lactic acidosis (e.g., weakness, tiredness, drowsiness, unusual muscle pain, trouble breathing, stomach pain with nausea, vomiting or diarrhea, feeling cold, dizziness, light-headedness, or slow or irregular heartbeat), stop taking Pms Metformin and get immediate medical attention.
Liver function: Decreased liver function has been linked to lactic acidosis. Pms Metformin is not recommended for people with severely reduced liver function. If you have moderately reduced liver function, discuss with your doctor how Pms Metformin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pms Metformin, and whether any special monitoring is needed.
Low blood sugar: Under usual circumstances, low blood sugar does not occur for people who take only metformin. Low blood sugar could occur when not enough food is eaten, especially when strenuous exercise is undertaken at the same time or when large amounts of alcohol have been consumed.
Reduced response: Over a period of time, you may become progressively less responsive to a particular treatment for diabetes because your diabetes worsens. If metformin fails to lower blood sugar to target levels, talk to your doctor. Your doctor may want to stop metformin or recommend another medication.
Surgery: Pms Metformin should be stopped temporarily for surgery (except for minor surgery where food and fluid intake is not restricted). You will be restarted on Pms Metformin once you are eating and drinking and your kidney function has been tested and is normal. Talk to your doctor for specific instructions.
Vitamin B12 levels: Pms Metformin may decrease vitamin B12 levels. Your doctor will monitor your B12 levels with blood tests while you are taking Pms Metformin.
Pregnancy: Pms Metformin should not be used during pregnancy. If you become pregnant while taking Pms Metformin, contact your doctor immediately.
Breast-feeding: Metformin is believed to pass into breast milk. Pms Metformin should not be used if you are breast-feeding.
Children: The safety and effectiveness of Pms Metformin have not been established for children.
Seniors: Kidney function often decreases with age. As a result, seniors may be more likely to experience side effects of Pms Metformin.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health.
Diabetes identification: It is important to either wear a bracelet (or necklace) or carry a card indicating you have diabetes and are taking medication to manage your blood glucose levels.
Heart problems: Trulicity (Dulaglutide) may increase heart rate and may affect how electrical impulses travel through the heart muscle. If you have heart disease (e.g., recent Heart Attack, Angina, heart failure) or an abnormal heart rhythm (e.g., heart block or fast heart rate), discuss with your doctor how Trulicity (Dulaglutide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trulicity (Dulaglutide), and whether any special monitoring is needed.
Intestinal problems: The safety and effectiveness of using Trulicity (Dulaglutide) have not been established for people who have problems with slowed movement of food through the digestive tract. If you have digestive system problems, discuss with your doctor how Trulicity (Dulaglutide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trulicity (Dulaglutide), and whether any special monitoring is needed.
Kidney function: The safety and effectiveness of using Trulicity (Dulaglutide) for people with reduced kidney function has not been studied. Ensure that you are drinking enough water to prevent dehydration if you experience nausea or vomiting with Trulicity (Dulaglutide). If you have reduced kidney function or Kidney Disease, discuss with your doctor how Trulicity (Dulaglutide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trulicity (Dulaglutide), and whether any special monitoring is needed.
Liver function: The safety and effectiveness of using Trulicity (Dulaglutide) for people with reduced liver function have not been studied. If you have reduced liver function or liver disease, discuss with your doctor how Trulicity (Dulaglutide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trulicity (Dulaglutide), and whether any special monitoring is needed.
Low blood glucose (Hypoglycemia): People who use Trulicity (Dulaglutide) and are also taking a sulfonylurea (e.g., Glyburide, Gliclazide) or insulin to control high blood sugar are more at risk of experiencing hypoglycemia (low blood sugar). If you experience symptoms of hypoglycemia such as a cold sweat, nervousness or shakiness, fast heartbeat, headache, hunger, confusion, lightheadedness, weakness, and numbness or tingling of the tongue or lips, contact your doctor. Your doctor may need to adjust the dose of your medication(s).
Pancreatitis (inflammation of the pancreas): Trulicity (Dulaglutide) can cause pancreatitis. If you experience symptoms of pancreatitis such as severe and persistent abdominal pain that may move to the back with or without vomiting, contact your doctor immediately. If you have previously had pancreatitis, discuss with your doctor how Trulicity (Dulaglutide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trulicity (Dulaglutide), and whether any special monitoring is needed.
Risk of thyroid cancer: In rare cases, people have developed thyroid cancer while using Trulicity (Dulaglutide). People with a personal or family history of thyroid cancer or people who have multiple endocrine neoplasia syndrome type 2 (a disease where people have tumours in more than one gland in their body) should not use Trulicity (Dulaglutide). If you develop symptoms of a thyroid tumour, such as difficulty swallowing, a mass in the neck or persistent hoarseness, contact your doctor as soon as possible.
Pregnancy: Trulicity (Dulaglutide) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Trulicity (Dulaglutide), contact your doctor immediately.
If you are planning to become pregnant, talk to your doctor about discontinuing Trulicity (Dulaglutide). You should not become pregnant for at least 4 weeks after stopping Trulicity (Dulaglutide), to give the medication enough time to completely leave the body.
Breast-feeding: It is not known if Trulicity (Dulaglutide) passes into breast milk. If you are a breast-feeding mother and are taking Trulicity (Dulaglutide), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Trulicity (Dulaglutide) have not been established for children.
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