Available in:Tablet
Dosage:10MG, 25MG
Manufacturer:Boehringer Ingelheim
Available in:Tablet
Dosage:15MG, 30MG, 45MG
Manufacturer:Takeda
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Do not give Jardiance (Empagliflozin) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Jardiance (Empagliflozin) if their doctor has not prescribed it.
The usual starting dose of Jardiance (Empagliflozin) is 10 mg taken by mouth once a day. Depending on how effectively it reduces your blood glucose, your doctor may increase the dose to 25 mg taken once a day.
Jardiance (Empagliflozin) may be taken at any time of the day, with or without food. The tablet must be swallowed whole. Do not cut or chew the tablets.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Jardiance (Empagliflozin) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is less than 12 hours until your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Jardiance (Empagliflozin) at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
The usual starting dose for adults is 15 mg or 30 mg taken once daily. Diet and exercise programs should be continued while taking Actos (Pioglitazone). Your doctor may decide to increase the dose of Actos (Pioglitazone) to 45 mg daily if lower doses do not sufficiently reduce your blood sugar levels. The use and dose of Actos (Pioglitazone) for children must be determined by their doctor.
Actos (Pioglitazone) may be taken with or without food, and should be taken daily and at regular intervals as prescribed by the doctor so that blood levels of the medication always remain in an effective range.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without talking to your doctor.
It is important to take Actos (Pioglitazone) exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Actos (Pioglitazone) at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Jardiance (Empagliflozin). If you are concerned about side effects, discuss the risks and benefits of Jardiance (Empagliflozin) with your doctor.
The following side effects have been reported by at least 1% of people taking Jardiance (Empagliflozin). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Jardiance (Empagliflozin).
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Actos (Pioglitazone). If you are concerned about side effects, discuss the risks and benefits of Actos (Pioglitazone) with your doctor.
The following side effects have been reported by at least 1% of people taking Actos (Pioglitazone). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Actos (Pioglitazone).
You should be aware of the signs of low blood sugar and what to do about it when taking any medication that reduces your blood sugar, including Actos (Pioglitazone). Signs of low blood sugar include:
If you experience symptoms of low blood sugar, eat glucose tablets or gel, corn syrup, honey, or sugar cubes, or drink juice or a non-diet soft drink, as discussed with your doctor or diabetes educator.
10 mg
Each pale yellow, round, biconvex and bevelled-edged, film-coated tablet, debossed with "S10" on one side and the Boehringer Ingelheim company symbol on the other side, contains 10 mg of Jardiance (Empagliflozin). Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, hydroxypropyl cellulose, hypromellose, lactose monohydrate, magnesium stearate, macrogol, microcrystalline cellulose, titanium dioxide, talc, and yellow ferric oxide.
25 mg
Each pale yellow, oval, biconvex, film-coated tablet, debossed with "S25" on one side and the Boehringer Ingelheim company symbol on the other side, contains 25 mg of Jardiance (Empagliflozin). Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, hydroxypropyl cellulose, hypromellose, lactose monohydrate, magnesium stearate, macrogol, microcrystalline cellulose, titanium dioxide, talc, and yellow ferric oxide.
15 mg
Each white to off-white, round, convex, non-scored tablet, with "ACTOS" printed on one side and "15" on the other, contains Actos (Pioglitazone) HCl equivalent to 15 mg of Actos (Pioglitazone). Nonmedicinal ingredients: carboxymethylcellulose calcium, hydroxypropyl cellulose, lactose monohydrate, and magnesium stearate.
30 mg
Each white to off-white, round, flat, non-scored tablet, with "ACTOS" printed on one side and "30" on the other, contains Actos (Pioglitazone) HCl equivalent to 30 mg of Actos (Pioglitazone). Nonmedicinal ingredients: carboxymethylcellulose calcium, hydroxypropyl cellulose, lactose monohydrate, and magnesium stearate.
45 mg
Each white to off-white, round, flat, non-scored tablet, with "ACTOS" printed on one side and "45" on the other, contains Actos (Pioglitazone) HCl equivalent to 45 mg of Actos (Pioglitazone). Nonmedicinal ingredients: carboxymethylcellulose calcium, hydroxypropyl cellulose, lactose monohydrate, and magnesium stearate.
Do not take Jardiance (Empagliflozin) if you:
Do not take Actos (Pioglitazone) if you:
There may be an interaction between Jardiance (Empagliflozin) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Jardiance (Empagliflozin). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
There may be an interaction between Actos (Pioglitazone) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Actos (Pioglitazone). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Jardiance (Empagliflozin)..
Health Canada has issued new information concerning the use of Jardiance (Jardiance (Empagliflozin)). To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Diabetic ketoacidosis (DKA): Jardiance (Empagliflozin) has been associated with DKA. This is a potentially life-threatening condition caused by not having enough insulin in the blood to use the glucose in the bloodstream. When this happens, the body starts to burn ketones for fuel and can make the blood acidic. This condition is more likely to develop if you are following a very low carbohydrate diet, are dehydrated, or have consumed a large amount of alcohol. Symptoms of DKA include:
If you experience these symptoms, get immediate medical help.
Drowsiness/reduced alertness: Jardiance (Empagliflozin) may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid these and other hazardous tasks until you have determined how Jardiance (Empagliflozin) affects you.
Fluid and electrolyte balance: Jardiance (Empagliflozin) causes increased urine production that may cause the levels of electrolytes such as potassium, sodium, magnesium, chloride, and calcium in the blood to change while taking Jardiance (Empagliflozin). If you experience symptoms of fluid and electrolyte imbalance such as muscle pains or cramps; Dry Mouth; numb hands, feet, or lips; or racing heartbeat, contact your doctor as soon as possible. Your doctor will do blood tests regularly to monitor the levels of these electrolytes in your blood while you are taking Jardiance (Empagliflozin).
Glucose control: When Jardiance (Empagliflozin) is taken along with other medications for diabetes, glucose levels may drop too far, causing confusion, cold sweats, cool and pale skin, headache, fast heartbeat, or weakness. Your doctor may suggest decreasing the dose of your other medications when you first start taking Jardiance (Empagliflozin). If you take other medications for diabetes, discuss with your doctor how Jardiance (Empagliflozin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Jardiance (Empagliflozin), and whether any special monitoring is needed.
Kidney function: Jardiance (Empagliflozin) may cause a decrease in kidney function. If you have reduced kidney function or kidney disease, discuss with your doctor how Jardiance (Empagliflozin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Jardiance (Empagliflozin), and whether any special monitoring is needed.
Low blood pressure: Jardiance (Empagliflozin) causes an increased amount of fluid to be removed from the body through the urine. As a result, it can cause decreases in blood pressure that may cause dizziness, especially when rising from a sitting or lying position. To reduce the possibility of dizziness or fainting, rise slowly from sitting or lying down.
Surgery: Jardiance (Empagliflozin) should be stopped temporarily for surgery (except for minor surgery where food and fluid intake is not restricted). You will be restarted on Jardiance (Empagliflozin) after surgery once you are eating and drinking again and your kidney function has been tested and is normal. Talk to your doctor for specific instructions.
Urinary tract infection: Jardiance (Empagliflozin) increases the risk of developing Urinary Tract Infections. If you experience symptoms of a urinary tract infection, such as increased need to urinate, burning sensation when urinating, cloudy urine, strong-smelling urine, or pelvic pain, contact your doctor.
Yeast infections: There is an increased risk of developing genital or vaginal yeast infections when taking Jardiance (Empagliflozin), as a result of increased glucose in the urine. This is more likely to occur for uncircumcised men and for people who have a history of yeast infections.
Pregnancy: Jardiance (Empagliflozin) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Jardiance (Empagliflozin), contact your doctor immediately.
Breast-feeding: It is not known if Jardiance (Empagliflozin) passes into breast milk. If you are a breast-feeding mother and are taking Jardiance (Empagliflozin), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Jardiance (Empagliflozin) have not been established for children.
Seniors: Seniors are at an increased risk of experiencing urinary tract infections and decreases in blood pressure while taking Jardiance (Empagliflozin).
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Actos (Pioglitazone).
Bladder: Taking Actos (Pioglitazone) may increase the risk of developing bladder cancer. If you have risk factors for bladder cancer, such as age, smoking, or someone in your family has had bladder cancer you may be more likely to develop this disease. Do not use Actos (Pioglitazone) if you have or have had bladder cancer.
If you experience symptoms such as blood or red colour in your urine, an urgent need to urinate, pain while urinating, or pain in the back or lower abdomen, talk to your doctor right away.
Fractures: Actos (Pioglitazone) has been associated with an increased incidence of bone fracture for female patients. You and your doctor should consider the risk of fractures. Talk to your doctor if you have any concerns.
Heart failure: Actos (Pioglitazone) can cause fluid buildup in the body, which may lead to Congestive Heart Failure. Actos (Pioglitazone) should not be used by anyone who has any degree of heart failure, or anyone who is at risk of heart failure (including people with swelling due to fluid buildup). If you develop fluid buildup or swelling, shortness of breath, fatigue, or excessive weight gain while taking Actos (Pioglitazone), you should consult your doctor immediately.
Liver: Although liver problems have not been observed with Actos (Pioglitazone), another similar medication has caused liver problems in a small number of people. You should report any signs of liver problems (abdominal or stomach pain, dark urine, loss of appetite, nausea or vomiting, unusual tiredness or weakness, or yellow eyes or skin) to your doctor at once.
Use with other diabetes medications: Actos (Pioglitazone) should not be used with insulin. It should not be used in combination (i.e., triple therapy) with both metformin and a sulfonylurea (e.g., glyburide, glicazide); however, it may be used with either metformin or a sulfonylurea.
Vision: Actos (Pioglitazone) may cause fluid to build up in the eye (macular edema) causing vision changes. If you experience any change to your vision, contact your doctor.
Pregnancy: Actos (Pioglitazone) has not been studied for use by pregnant women. Actos (Pioglitazone) should not be used during pregnancy. In general, blood sugar should be controlled during pregnancy by using insulin injections. If you become pregnant while taking Actos (Pioglitazone), contact your doctor immediately.
Breast-feeding: It is not known if Actos (Pioglitazone) passes into breast milk. If you are a breast-feeding mother and are taking Actos (Pioglitazone), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Actos (Pioglitazone) have not been established for children.
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