Viberzi (Eluxadoline) belongs to the class of medications called opioid receptor agonist/antagonists. It works in the bowel to regulate muscle activity and slow the rate that material passes through the digestive system.

Viberzi (Eluxadoline) is used to treat irritable bowel syndrome with Diarrhea in adults (IBS-D).

Viberzi (Eluxadoline) may be available under multiple brand names and/or in several different forms. Any specific brand name of Viberzi (Eluxadoline) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Viberzi (Eluxadoline) may not be used for all of the conditions discussed here.

Your doctor may have suggested Viberzi (Eluxadoline) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Viberzi (Eluxadoline), speak to your doctor. Do not stop taking Viberzi (Eluxadoline) without consulting your doctor.

Do not give Viberzi (Eluxadoline) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Viberzi (Eluxadoline) if their doctor has not prescribed it.

Free Delivery

Your medication is delivered directly to you at no added cost. We even offer same-day delivery in select locations.

The recommended adult dose of Viberzi (Eluxadoline) is 100 mg taken by mouth 2 times daily. People over the age of 65 years should be started at a dose of 75 mg 2 times daily. Viberzi (Eluxadoline) should be taken with food.

Depending on how well the medication is tolerated, your doctor may decrease the dose.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Viberzi (Eluxadoline) exactly as prescribed by your doctor. If you miss a dose, and it is less than 4 hours since the missed dose, take it as soon as possible and continue with your regular schedule. If it is more than 4 hours since the missed dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Viberzi (Eluxadoline) at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Viberzi (Eluxadoline). If you are concerned about side effects, discuss the risks and benefits of Viberzi (Eluxadoline) with your doctor.

The following side effects have been reported by at least 1% of people taking Viberzi (Eluxadoline). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• bloating
• constipation
• dizziness
• fatigue
• gas
• nausea
• sleepiness
• vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• abdominal pain
• nausea and vomiting (accompanied by other symptoms)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• severe constipation
• symptoms of pancreatitis (e.g., abdominal pain, nausea, vomiting)
• symptoms of a serious allergic reaction (such as Fever, swollen glands, yellowing of skin or eyes, or flu-like symptoms with skin rash or blistering)
• symptoms of spasm of the sphincter of Oddi (e.g., new or worsening belly pain, nausea, vomiting, or sudden pain in the upper right abdomen)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Viberzi (Eluxadoline).

Personalized PocketPacks

We sort your medication into clearly labeled, individual packs so you can be sure you're taking the right dose at the right time.

75 mg
Each pale yellow-to-light tan, capsule-shaped tablet debossed with "FX75" on one side, contains 75 mg of Viberzi (Eluxadoline). Nonmedicinal ingredients: colloidal silica, crospovidone, mannitol, magnesium stearate, silicified microcrystalline cellulose, and Opadry II (iron oxide red, iron oxide yellow, polyethylene glycol, partially hydrolyzed polyvinyl alcohol, talc, and titanium dioxide).

100 mg
Each pink-orange-to-peach, capsule-shaped tablet, debossed with "FX100" on one side contains 100 mg of Viberzi (Eluxadoline). Nonmedicinal ingredients: colloidal silica, crospovidone, mannitol, magnesium stearate, silicified microcrystalline cellulose, and Opadry II (iron oxide red, iron oxide yellow, polyethylene glycol, partially hydrolyzed polyvinyl alcohol, talc, and titanium dioxide).

Do not take Viberzi (Eluxadoline) if you:

• are allergic to Viberzi (Eluxadoline) or any ingredients of the medication
• have or may have a biliary duct blockage
• do not have a gallbladder
• consume more than 3 alcoholic drinks daily
• are alcoholic, have an alcohol addiction, or abuse alcohol
• have a history of inflammation of the pancreas (pancreatitis)
• have decreased liver function
• have a history of chronic or severe Constipation
• have or have had an obstruction of the digestive tract
• are taking certain medications:
• Cyclosporine
• Gemfibrozil
• HIV protease inhibitors (e.g., atazanavir, lopinavir, ritonavir, saquinavir)
• rifampin

Discreet Packaging

Your privacy is important. That's why we send your medication inside a plain delivery box so no one will know what's inside.

There may be an interaction between Viberzi (Eluxadoline) and any of the following:

• aclidinium
• alcohol
• amoxapine
• antihistamines (e.g., cetirizine, doxylamine, Diphenhydramine, Hydroxyzine, Loratadine)
• antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
• atropine
• azelastine
• belladonna
• Benztropine
• Cyclobenzaprine
• cyclosporine
• Darifenacin
• Disopyramide
• Eltrombopag
• Fesoterodine
• Flavoxate
• gemfibrozil
• glycopyrrolate
• Hepatitis C antivirals (e.g., dasabuvir, ombitasvir, paritaprevir, ritonavir)
• HIV protease inhibitors (e.g., atazanavir, lopinavir, ritonavir, saquinavir)
• ipratropium
• ketotifen
• Loperamide
• monoamine oxidase inhibitors (M.O.S. e.g., Moclobemide, Phenelzine, Rasagiline, Selegiline, Tranylcypromine)
• narcotic pain relievers (e.g., Codeine, Fentanyl, Morphine, Oxycodone)
• orphenadrine
• Oxybutynin
• Prochlorperazine
• quinidine
• quinine
• rifampin
• Rosuvastatin
• scopolamine
• Solifenacin
• Teriflunomide
• tiotropium
• Tolterodine
• Tramadol
• tranylcypromine
• tricyclic antidepressants (e.g., Amitriptyline, Clomipramine, Desipramine, Trimipramine)
• umeclidinium

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Viberzi (Eluxadoline). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Viberzi (Eluxadoline).

Constipation: Viberzi (Eluxadoline) may cause severe constipation in some people. If you experience symptoms of severe constipation such as difficulty passing stool, sudden stomach pain, nausea, vomiting, or a bloated stomach, contact your doctor immediately.

Dependence and drug abuse: Although Viberzi (Eluxadoline) primarily works in the digestive tract, it can cause euphoria (a false sense of extreme well-being). It is possible to develop a psychological need for Viberzi (Eluxadoline).

Drowsiness/reduced alertness: Viberzi (Eluxadoline) may affect the mental or physical abilities needed to drive or operate machinery. Avoid driving, operating machinery, or performing other potentially hazardous tasks until you have determined how you are affected by Viberzi (Eluxadoline).

Liver function: Liver disease or reduced liver function may cause Viberzi (Eluxadoline) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Viberzi (Eluxadoline) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Viberzi (Eluxadoline), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Viberzi (Eluxadoline).

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Pancreatitis: Viberzi (Eluxadoline) can cause the pancreas to become inflamed. If you have a history of pancreatitis, discuss with your doctor how Viberzi (Eluxadoline) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Viberzi (Eluxadoline), and whether any special monitoring is needed.

Report signs of pancreatitis such as abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, or swollen abdomen to your doctor immediately.

If you have a history of pancreatitis, gallstones, Alcoholism, or high triglycerides, you may be more at risk of experiencing this.

Sphincter of Oddi: The sphincter of Oddi is a muscular valve that controls the passage of digestive juices from the pancreas and gall bladder to the small intestine. In uncommon instances, this muscle can spasm, increasing the risk of inflammation of the pancreas or decreased liver function. If you experience symptoms of spasm of the sphincter of Oddi, such as nausea, vomiting, and sudden pain in the upper right hand side of the abdomen, possibly radiating toward the back, get medical help immediately.

Pregnancy: Viberzi (Eluxadoline) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Viberzi (Eluxadoline), contact your doctor immediately.

Breast-feeding: It is not known if Viberzi (Eluxadoline) passes into breast milk. If you are a breast-feeding mother and are taking Viberzi (Eluxadoline), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Viberzi (Eluxadoline) have not been established for children.

Seniors: People over the age of 65 years may experience more side effects from Viberzi (Eluxadoline).

Automatic Refills

We manage your refills and get in touch with your doctors for prescription renewals so that you always have the medication you need.