The recommended dose of Skyrizi (Risankizumab) is 150 mg injected subcutaneously (under the skin). Each 150 mg dose is made up of 2 separate injections of 75 mg. After the first dose of 150 mg, a second dose is given after 4 weeks. After that, riskankizumab is given every 12 weeks. Skyrizi (Risankizumab) is administered by subcutaneous injection in the thigh, upper arm, or abdomen. A full dose consists of 2 injections (of 75 mg each), given one right after the other. Inject the second syringe at least 3 cm (1 inch) away from the first injection. It is important to change the injection site you're using, rotating between sites, to reduce the risk of fat wasting at the injection site. Avoid injecting into areas that are tender, bruised, or affected by psoriasis.
The solution should be clear-to-slightly milky and colourless-to-slightly yellow. It is normal to see a few tiny, white or clear particles in the solution. If the solution is discoloured or contains flakes or large particles, do not use the contents of the pre-filled syringe. Instead, use a fresh syringe. Allow the medication to warm to room temperature for 15 to 30 minutes before you inject it.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Skyrizi (Risankizumab) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
If you are receiving Skyrizi (Risankizumab) at the doctor's office and you miss an appointment to receive Skyrizi (Risankizumab), contact your doctor as soon as possible to reschedule your appointment.
Store Skyrizi (Risankizumab) in the refrigerator, protect it from light and moisture, and keep it out of the reach of children. Do not let Skyrizi (Risankizumab) freeze.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.