Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Apo Ismn (Isosorbide-mononitrate).
Drowsiness/reduced alertness: Apo Ismn (Isosorbide-mononitrate) may cause faintness or dizziness. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how Apo Ismn (Isosorbide-mononitrate) affects you.
Heart disease: Isosorbide-5-mononitrate may cause some symptoms of heart disease to become worse. If you have heart problems caused by not enough oxygen being available for the heart or other organs of the body, discuss with your doctor how Apo Ismn (Isosorbide-mononitrate) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Ismn (Isosorbide-mononitrate), and whether any special monitoring is needed.
Low blood pressure: Some people who take Apo Ismn (Isosorbide-mononitrate) experience symptoms of a severe decrease in blood pressure, such as weakness or dizziness. This is more likely to happen when rising suddenly from a sitting or lying position. If it persists or if you faint, contact your doctor. People who have or have had heart disease, Stroke, "mini-stroke", or are at risk of experiencing low blood pressure (e.g., dehydration, taking medications for high blood pressure) should discuss with their doctor how Apo Ismn (Isosorbide-mononitrate) may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Apo Ismn (Isosorbide-mononitrate), and whether any special monitoring is needed.
Tolerance: With continued use, isosorbide-5-mononitrate may stop having beneficial effects because the body gets used to it (i.e., develops a tolerance). Call your doctor if at any time you feel that your angina attacks are getting worse or happening more often.
Withdrawal: Stopping Apo Ismn (Isosorbide-mononitrate) suddenly may occasionally aggravate chest pain or other symptoms of angina. To avoid possible withdrawal effects, Apo Ismn (Isosorbide-mononitrate) should be gradually reduced and not stopped suddenly. Do not change the way you are taking Apo Ismn (Isosorbide-mononitrate) without speaking to your doctor.
Pregnancy: Studies demonstrating the safety and effectiveness of using isosorbide-5-mononitrate during pregnancy are not available. Apo Ismn (Isosorbide-mononitrate) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Apo Ismn (Isosorbide-mononitrate), contact your doctor immediately.
Breast-feeding: It is not known if isosorbide-5-mononitrate passes into breast milk. If you are a breast-feeding mother and are taking Apo Ismn (Isosorbide-mononitrate), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Apo Ismn (Isosorbide-mononitrate) have not been established for children. Its use by this age group is not recommended.
Seniors: Seniors may be more likely to experience dizziness or lightheadedness while taking Apo Ismn (Isosorbide-mononitrate).
