Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Fondaparinux.
Bleeding: Fondaparinux can increase the risk of unwanted or uncontrolled bleeding, particularly if you have a bleeding disorder, ulcers of the digestive system or a recent episode of bleeding after brain, spine, or eye surgery. People who weigh less than 50 kg may also have an increased risk of bleeding. If you believe you may have an increased risk of bleeding problems, discuss with your doctor how Fondaparinux may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Fondaparinux, and whether any special monitoring is needed.
Kidney function: Kidney Disease or reduced kidney function may cause Fondaparinux to build up in the body, causing side effects. If you have reduced kidney function or kidney disease, discuss with your doctor how Fondaparinux may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Fondaparinux, and whether any special monitoring is needed.
Latex allergy: The needle shield of the pre-filled syringe contains dry natural latex rubber. If you are allergic to latex, this may cause an allergic reaction.
Spinal/epidural hematomas: There have been cases of spinal bleeding and blood clots when antithrombotic medications are used along with spinal or epidural anesthesia. These spinal blood clots may lead to long-term or permanent paralysis. The risk may be greater if people are taking other medications that affect blood clotting (e.g., nonsteroidal anti-inflammatory drugs [NSAIDs] such as Naproxen or Ibuprofen, or other anticoagulants), or in people who require repeated epidural or spinal procedures. If you notice a sudden inability to move your body or sudden back pain or tenderness, get medical help immediately.
Pregnancy: Fondaparinux should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Fondaparinux, contact your doctor immediately.
Breast-feeding: It is not known if fondaparinux passes into breast milk. If you are a breast-feeding mother and are taking Fondaparinux, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Fondaparinux have not been established for children less than 17 years old.
Seniors: People over the age of 65 years old may be more at risk of bleeding from Fondaparinux.