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Clobex

Clobex

(clobetasol-propionate)

Clobetasol is a topical (skin-applied) corticosteroid medication used to treat skin conditions that have not responded well to other corticosteroids, including severe psoriasis and eczematous dermatitis. The scalp lotion and shampoo are used to treat psoriasis and seborrheic dermatitis occurring on the scalp.

Available form

Dosage

Shampoo

0.05%

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Clobex information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

Cream and ointment: Apply the medication sparingly to cover the affected area and gently rub it into the skin 2 or 3 times daily. The total dose applied should not be more than 50 g in a week. Use Clobex (Clobetasol-propionate) with caution on lesions near the eye. Take care to prevent it from getting into the eye.

Lotion: Apply the lotion to the affected areas of skin 2 times daily and rub it in gently and completely. The total dose should not exceed 50 g (50 mL) in a week.

Scalp lotion: Apply the lotion 1 or 2 times daily to the affected areas of the scalp and rub in gently. The total dose should not exceed 50 mL in a week. Clobetasol scalp applications should not be used near an open flame.

Foam: Apply a thin layer of foam 2 times daily to the affected areas of the skin and rub in gently until the foam is absorbed. The foam is extremely flammable, so avoid fire, flames, sparks or smoking during and immediately after applying. The total dose applied should not exceed 50 g in a week.

Spray: Apply the solution 2 times daily to the affected areas of the skin and rub in gently. The total dose should not exceed 50 mL in a week.

Shampoo: A thin film of clobetasol shampoo should be applied directly to the affected area of the scalp once daily. The shampoo is applied to the lesions on dry scalp and rubbed in gently. Leave it on for 15 minutes before wetting the hair, lathering, and rinsing. The total dose applied should not be more than 50 mL in a week.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

When clobetasol 17 - propionate is used over extensive areas for prolonged periods or under dressings that don't breathe, it is possible that enough medication will absorb into the bloodstream to cause unwanted side effects. Therefore, it is advisable to use clobetasol 17 - propionate only for brief periods and to stop using it as soon as the problem clears.

Clobex (Clobetasol-propionate) should not be used under dressings that don't breathe.

If you have not noticed improvement in your skin after a week, stop using the medication and contact your doctor.

It is important to use Clobex (Clobetasol-propionate) exactly as prescribed by your doctor. If you miss a dose, apply it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Clobex (Clobetasol-propionate) at room temperature, protect it from light, and keep it out of the reach of children. The spray is flammable and should be kept away from heat or flame.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Clobex (Clobetasol-propionate). If you are concerned about side effects, discuss the risks and benefits of Clobex (Clobetasol-propionate) with your doctor.

The following side effects have been reported by at least 1% of people taking Clobex (Clobetasol-propionate). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

burning, dryness, irritation, itching, or redness of skin (usually mild and temporary)
headache
increased redness or scaling of skin sores (usually mild and temporary)
skin colour changes
skin infection
skin rash (usually mild and temporary)
softening and tearing of the skin
thinning of skin with easy bruising
tingling, prickling feeling of the skin

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

acne or oily skin
general feeling of being unwell
lack of healing of skin condition
painful, red, or itchy pus-containing blisters in hair follicles
unusual increase in hair growth, especially on the face
visible lines or small blood vessels under the skin
unusual loss of hair, especially on the scalp
vision changes

The following side effects may occur if Clobex (Clobetasol-propionate) is used improperly or for a long time:

blurring or loss of vision (occurs gradually if certain products have been used near the eye)
filling or rounding out of the face
increased blood pressure
irregular heartbeat
irregular menstrual periods
irritability
irritation of skin around mouth
loss of appetite
Depression
muscle cramps, pain, or weakness
rapid weight gain or loss
stomach bloating, burning, cramping, or pain
swelling of feet or lower legs
unusual bruising
unusual decrease in sexual desire or ability (in men)
unusual tiredness or weakness
vomiting
weakness of the arms, legs, or trunk (severe)
worsening of infections

Stop using the medication and seek immediate medical attention if any of the following occur:

symptoms of a serious allergic reaction (e.g., difficulty breathing, dizziness, itching, rash, swelling)
symptoms of high levels of corticosteroids in the blood stream (e.g., fatigue, increased thirst and urination, irritability, muscle weakness)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are using Clobex (Clobetasol-propionate).

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Clobex (Clobetasol-propionate).

Inform all of your doctors that you are using topical (skin-applied) corticosteroids.

Absorption: When clobetasol 17 - propionate is used over extensive areas for prolonged periods and under dressings that don't breathe, it is possible that enough medication will absorb into the bloodstream to cause unwanted side effects. Therefore, it is advisable to use Clobex (Clobetasol-propionate) for brief periods only and to stop using it as soon as the problem clears. Talk to your health care provider about how long you should use Clobex (Clobetasol-propionate).

Diabetes: When clobetasol 17-propionate is used over large areas of the body for prolonged periods or under dressings that don't breathe it is possible that enough medication will absorb into the bloodstream to affect blood sugar levels. If you have diabetes, your doctor should closely monitor your condition while you are using clobetasol 17-propionate, as it may affect blood sugar control (either increase or decrease blood sugar levels).

Eyes: Use Clobex (Clobetasol-propionate) with care on lesions close to the eye. Getting the medication in the eye can increase the risk of increased eye pressure, Glaucoma, or Cataracts.

Infection: Topical corticosteroids may increase the risk of developing a skin infection. Contact your doctor if you notice any increased redness, swelling, heat or pain around the area where the medication is applied as these are possible signs of infection.

Medical treatment: Inform all health professionals involved in your care that you have been using a topical (skin-applied) corticosteroid.

Thinning of skin: Using topical corticosteroid medications for a long period of time can cause skin to thin or soften or cause stretch marks. Your doctor may recommend you stop using Clobex (Clobetasol-propionate) once in a while or to apply to one area of the body at a time. Suddenly stopping corticosteroid medication may cause psoriasis to return.

Pregnancy: Clobex (Clobetasol-propionate) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using Clobex (Clobetasol-propionate), contact your doctor immediately.

Breast-feeding: Clobex (Clobetasol-propionate) may pass into breast milk. If you are a breast-feeding mother and are using clobetasol 17-propionate, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: Children are more likely to experience absorption of Clobex (Clobetasol-propionate) into the bloodstream, resulting in unwanted effects. The safety and effectiveness of using Clobex (Clobetasol-propionate) have not been established for children. Its use by children is not recommended.

Seniors: People over the age of 65 may need to use a smaller amount of Clobex (Clobetasol-propionate) or use it less often.

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