Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Apo Tiaprofenic (Tiaprofenic-acid).
HEALTH CANADA ADVISORY
June 8, 2021
Health Canada has issued new information concerning the use of non-steroidal anti-inflammatory drugs (NSAIDs). To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
A previous advisory on non-steroidal anti-inflammatory drugs (NSAIDs) was issued on October 30, 2020.
Cardiovascular disease: As with other nonsteroidal anti-inflammatory drugs (NSAIDs), tiaprofenic acid may cause blood pressure to increase, Stroke, or Heart Attack. People with any heart or circulatory disease should discuss with their doctor how Apo Tiaprofenic (Tiaprofenic-acid) may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Apo Tiaprofenic (Tiaprofenic-acid), and whether any special monitoring is needed.
Drowsiness/reduced alertness: Headache, dizziness, and lightheadedness have been reported by some people taking Apo Tiaprofenic (Tiaprofenic-acid). Do not drive vehicles or undertake other potentially hazardous activities until you have determined that Apo Tiaprofenic (Tiaprofenic-acid) does not affect you in this way.
Fluid retention: As with many other NSAIDs, fluid retention has been reported. Tiaprofenic acid should be used with caution by anyone who:
- is recovering from surgical operations under general anesthesia
- has any other condition that might lead to fluid retention
- has certain heart conditions
- has high blood pressure
- has Kidney Disease
People with any of the above conditions should discuss with their doctor how Apo Tiaprofenic (Tiaprofenic-acid) may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Apo Tiaprofenic (Tiaprofenic-acid), and whether any special monitoring is needed.
Kidney function: Tiaprofenic acid has occasionally been known to cause kidney damage. People with reduced kidney function or kidney disease should discuss with their doctor how Apo Tiaprofenic (Tiaprofenic-acid) may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Apo Tiaprofenic (Tiaprofenic-acid), and whether any special monitoring is needed. If you are taking the medication for a long period of time, your doctor may recommend kidney function tests.
Liver function: Other medications from the same group as tiaprofenic acid (NSAIDs) have occasionally caused liver damage. People with reduced liver function or liver disease should discuss with their doctor how Apo Tiaprofenic (Tiaprofenic-acid) may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Apo Tiaprofenic (Tiaprofenic-acid), and whether any special monitoring is needed.
Stop taking the medication and contact your doctor as soon as possible if you notice signs of liver damage, such as yellow eyes or skin, abdominal pain, itchy skin, pale stools, or dark urine. Your doctor may recommend regular liver function tests if you are taking Apo Tiaprofenic (Tiaprofenic-acid) for a long period of time.
Ulcers: Tiaprofenic acid may increase the risk of ulcers in the stomach and intestines. It should be taken under close medical supervision by people prone to irritation of the stomach and intestines, particularly those people who have had a stomach ulcer, blood in the stools, or diverticulosis or another inflammatory disease of the stomach or intestines (such as ulcerative colitis or Crohn's Disease). In these cases, the doctor must weigh the benefits of treatment against the possible risks. Stop taking the medication and seek immediate medical attention if you develop symptoms of a bleeding ulcer such as dark tarry stools, blood in the stools, or the vomiting up of blood or material that looks like coffee grounds.
Pregnancy: Tiaprofenic acid should not be used during early pregnancy unless the benefits outweigh the risks. If it is taken close to the end of pregnancy, it may prolong labour. If you become pregnant while taking Apo Tiaprofenic (Tiaprofenic-acid), contact your doctor immediately.
Breast-feeding: Tiaprofenic acid passes into breast milk. If you are a breast-feeding mother and are taking tiaprofenic acid, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of Apo Tiaprofenic (Tiaprofenic-acid) have not been established for children.
Seniors: Seniors who take Apo Tiaprofenic (Tiaprofenic-acid) should be closely monitored by their doctors. Seniors may be more likely to develop side effects to tiaprofenic acid and may require a lower dose.
