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Vyzulta

Vyzulta

(latanoprostene-bunod)

Latanoprostene belongs to a class of medications called prostaglandin analogs. It works to reduce the pressure in the eye by allowing fluid in the eye to flow out of the eye more easily.

Available form

Dosage

Eye Drops

0.024%

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Vyzulta information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The usual adult dose of latanoprostene is 1 drop in the affected eye(s), once daily, preferably in the evening. Vyzulta (Latanoprostene-bunod) should not be used more than once a day, as this will reduce its effectiveness.

Ask your doctor or pharmacist to show you the correct way to use the eye drops. Vyzulta (Latanoprostene-bunod) is for external use only. Do not allow the dropper tip of the bottle to touch your eye or the surrounding area, because this could contaminate the tip with common bacteria known to cause Eye Infections. Serious damage to the eye may occur if your eye drop solution has become contaminated.

Remove contact lenses before putting the drops in your eye(s). You can reinsert them 15 minutes after you have put the latanoprostene eye drops in.

Latanoprostene eye drops may be used with other eye medications intended to reduce pressure inside the eye. If you are using more than one type of eye drop, use the medications at least 5 minutes apart.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Vyzulta (Latanoprostene-bunod) exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Vyzulta (Latanoprostene-bunod) at room temperature, protect it from light and moisture, and keep it out of the reach of children. Any medication remaining in the bottle 8 weeks after opening must be safely discarded.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Vyzulta (Latanoprostene-bunod).

Eye changes: Latanoprostene may gradually change the colour of the eye, increasing the amount of brown pigment in the iris by increasing the number of melanosomes (pigment granules). The long-term effects on the eye and the chances of injury to the eye are currently unknown. The change in colour may be permanent. This effect has mostly been seen in patients with mixed-coloured eyes (e.g., blue-brown, grey-brown, green-brown, or yellow-brown). In patients with uniformly blue, grey, green, or brown eyes, the change has only rarely been seen. The change in colour occurs slowly, and may not be noticeable for several months to years. Latanoprostene has also been reported to cause darkening, thickening, and lengthening of eyelashes, as well as darkening of the eyelid.

Other eye conditions: The safety of using latanoprostene eye drops if you have other eye conditions may not be well known. If you have other eye conditions such as macular edema, uveitis or lens problems, or a history of herpetic keratitis, discuss with your doctor how latanoprostene may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Vyzulta (Latanoprostene-bunod), and whether any special monitoring is needed.

Kidney or liver function: Vyzulta (Latanoprostene-bunod) has not been studied for use by people with impaired kidney or liver function. If you have impaired kidney or liver function, discuss with your doctor how latanoprostene may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Vyzulta (Latanoprostene-bunod), and whether any special monitoring is needed.

Contact lenses: Remove contact lenses before instilling these eye drops. Lenses can be reinserted 15 minutes after using the eye drops.

Pregnancy: Vyzulta (Latanoprostene-bunod) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Vyzulta (Latanoprostene-bunod), contact your doctor immediately.

Breast-feeding: Vyzulta (Latanoprostene-bunod) may pass into breast milk. If you are a breast-feeding mother and are taking latanoprostene, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Vyzulta (Latanoprostene-bunod) have not been established for children and adolescents less than 16 years of age.

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