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RUKOBIA

RUKOBIA

(fostemsavir)

RUKOBIA (Fostemsavir) belongs to the class of medications called antiretrovirals. It is used in addition to other HIV medications to treat the infection caused by the human immunodeficiency virus (HIV) that has become resistant to multiple other medications used to treat HIV infection.

Available form

Dosage

12-Hour Release Tablet

600MG

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RUKOBIA information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The recommended dose of RUKOBIA (Fostemsavir) is 600 mg (1 tablet) taken by mouth, 2 times daily. It is taken in combination with other anti-HIV medications.

RUKOBIA (Fostemsavir) may be taken with or without food. Swallow the tablets whole with some water and do not crush or chew them.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take RUKOBIA (Fostemsavir) exactly as prescribed by your doctor.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store RUKOBIA (Fostemsavir) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use RUKOBIA (Fostemsavir).

Heart rhythm: RUKOBIA (Fostemsavir) can cause changes to the normal rhythm of the heart, including an irregular heartbeat called QT prolongation, when more than the recommended dose is taken. QT prolongation is a serious life-threatening condition that can cause fainting, seizures, and sudden death.

People with heart failure, Angina, low potassium or magnesium levels, or those who are taking other medications that can cause changes to the heart rhythm, may be at risk of developing an irregular heartbeat. If you have heart problems, or you are taking other medications, discuss with your doctor how RUKOBIA (Fostemsavir) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of RUKOBIA (Fostemsavir), and whether any special monitoring is needed.

Hepatitis B and C: People who have hepatitis B or Hepatitis C may be more likely to experience decreased liver function and side effects involving the liver when they are taking RUKOBIA (Fostemsavir). If you have hepatitis B or C, discuss with your doctor how RUKOBIA (Fostemsavir) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of RUKOBIA (Fostemsavir), and whether any special monitoring is needed.

Immune reconstitution inflammatory syndrome: RUKOBIA (Fostemsavir) may cause immune reconstitution syndrome, where signs and symptoms of inflammation from previous infections appear. These symptoms occur soon after starting anti-HIV medication and can vary. They are thought to occur because of the immune system improving and being able to fight infections that have been present without symptoms (such as pneumonia, herpes or Tuberculosis). Report any new symptoms to your doctor immediately.

Stopping the medication: If you stop taking RUKOBIA (Fostemsavir), your HIV infection could get worse. Take the medication exactly as prescribed by your doctor and do not stop taking the medication without checking with your doctor first.

Pregnancy: RUKOBIA (Fostemsavir) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking RUKOBIA (Fostemsavir), contact your doctor immediately.

Breast-feeding: It is not known if RUKOBIA (Fostemsavir) passes into breast milk.Women with HIV infection are cautioned against breast-feeding because of the risk of passing HIV to a baby who does not have the infection, since the virus can be transmitted through breast milk.

Children: The safety and effectiveness of using RUKOBIA (Fostemsavir) have not been established for children.

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