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Renagel

Renagel

(sevelamer-hydrochloride)

Sevelamer hydrochloride belongs to the class of medications called phosphate binders. Phosphate is made up mostly of the mineral phosphorus, which is an important component of normal bone structure, cell metabolism, and cell function.

Available form

Dosage

Tablet

800MG

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Renagel information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The dose of sevelamer hydrochloride depends on the amount of phosphorus that is present in the blood. The starting dose can range from 2.4 g to 4.8 g each day. Total daily doses of sevelamer hydrochloride are usually divided according to meal sizes, where higher doses of sevelamer hydrochloride are given with larger meals.

Your doctor may gradually increase the total daily dose of sevelamer hydrochloride according to the phosphorus level in your blood. Tablets should be taken immediately before meals or with meals. Swallow the tablets whole. Do not bite, chew, or break apart the tablet before swallowing.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use Renagel (Sevelamer-hydrochloride) exactly as prescribed by your doctor. If you miss a dose of Renagel (Sevelamer-hydrochloride), skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Renagel (Sevelamer-hydrochloride) at room temperature, protect it from moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Renagel (Sevelamer-hydrochloride). If you are concerned about side effects, discuss the risks and benefits of Renagel (Sevelamer-hydrochloride) with your doctor.

The following side effects have been reported by at least 1% of people taking Renagel (Sevelamer-hydrochloride). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

Constipation
Diarrhea
heartburn or indigestion
itchiness
nausea
rash
vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

difficulty swallowing
signs of bowel obstruction (e.g., abdominal discomfort, cramps, gas pain, difficulty passing stools, nausea, vomiting)
signs of inflammation in the digestive system (e.g., pain in the lower left abdomen, Fever, nausea, diarrhea, or constipation)
signs of lower levels of calcium (e.g., muscle cramps, pain, dry skin)

Stop taking the medication and seek immediate medical attention if any of the following occur:

signs of an allergic reaction (shortness of breath or difficulty breathing; Hives; swelling of the eyes, mouth, lips, or throat)
signs of a blockage in the digestive system (e.g., abdominal cramping, gas pain, nausea, vomiting after meals, excessive burping)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Renagel (Sevelamer-hydrochloride).

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Renagel (Sevelamer-hydrochloride).

Gastrointestinal disorders: Sevelamer may cause a bowel obstruction to form. If you have gastrointestinal disorders (e.g., dysphagia [difficulty swallowing], severe disorders of movement in the gastrointestinal tract [i.e., the esophagus, stomach, and bowel]) or you have had major gastrointestinal surgery, discuss with your doctor how Renagel (Sevelamer-hydrochloride) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Renagel (Sevelamer-hydrochloride), and whether any special monitoring is needed.

Low calcium: People with kidney disease may develop a condition called hypocalcemia (low calcium levels in the blood). While you are taking Renagel (Sevelamer-hydrochloride), your doctor will regularly monitor your blood calcium levels. If you experience signs or symptoms of low blood calcium levels, such as muscle cramping or ache, dry skin or a feeling of pins and needles in your fingers, lips, tongue, or feet, contact your doctor as soon as possible.

Pregnancy: Renagel (Sevelamer-hydrochloride) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Renagel (Sevelamer-hydrochloride), contact your doctor immediately.

Breast-feeding: It is not known if sevelamer hydrochloride passes into breast milk. If you are a breast-feeding mother and are taking Renagel (Sevelamer-hydrochloride), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children and adolescents: The safety and effectiveness of using Renagel (Sevelamer-hydrochloride) have not been established for children and adolescents less than 18 years of age.

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