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Pariet

Pariet

(rabeprazole)

Pariet (Rabeprazole) belongs to the class of medications known as proton pump inhibitors (PPIs). It works by slowing or preventing the production of acid in the stomach.

Available form

Dosage

Enteric-Coated Tablet

10MG, 20MG

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Pariet information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The dose of Pariet (Rabeprazole) used depends on the condition being treated.

To treat non-erosive reflux disease (NERD), the recommended adult dose of Pariet (Rabeprazole) is 10 mg to 20 mg, taken once daily for up to 4 weeks.

To treat gastroesophageal reflux disease (GERD) with esophagitis, the recommended adult dose of Pariet (Rabeprazole) is 20 mg, taken once daily. The recommended adult dose for maintaining long-term healing of GERD is 10 mg to 20 mg, taken once daily. The usual length of treatment for GERD is 4 to 8 weeks.

To treat duodenal ulcer, the recommended adult dose of Pariet (Rabeprazole) is 20 mg, taken once daily for a period of up to 4 weeks.

To treat gastric or stomach ulcer, the recommended adult dose of Pariet (Rabeprazole) is 20 mg, taken once daily for a period of up to 6 weeks.

To treat ulcer caused by Helicobacter pylori infection, the recommended adult dose is 20 mg, taken twice daily for 7 days in combination with 2 antibiotics, usually amoxicillin and clarithromycin. If you are taking Pariet (Rabeprazole) in combination with antibiotic drugs, it is important that you take all medications at the correct time of day and for the entire treatment period as recommended by your doctor.

To treat Zollinger-Ellison syndrome, the recommended adult starting dose of Pariet (Rabeprazole) is 60 mg, taken once daily. Some people may require higher doses. Your doctor will adjust the dose of Pariet (Rabeprazole) as needed.

Pariet (Rabeprazole) delayed release tablet has been designed to work throughout the day, and therefore needs to be taken only once daily. Pariet (Rabeprazole) may be taken with or without food. Swallow the tablets whole with a beverage. Do not chew, crush, or split the tablets.

Most people will experience some improvements in symptoms 1 to 2 weeks after starting Pariet (Rabeprazole). It may take up to 4 weeks for people to experience maximum benefit from Pariet (Rabeprazole).

Keep taking Pariet (Rabeprazole) and finish all the tablets as recommended by your doctor even if you start to feel better. If the symptoms that were causing you problems have not gone away by the time you finish your medication or as discussed with your doctor, call your doctor.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Pariet (Rabeprazole) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Pariet (Rabeprazole) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Pariet (Rabeprazole). If you are concerned about side effects, discuss the risks and benefits of Pariet (Rabeprazole) with your doctor.

The following side effects have been reported by at least 1% of people taking Pariet (Rabeprazole). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

Diarrhea (mild)
dizziness
headache
itchiness
rash

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

abnormal or fast heart beat
blood in stool
a fracture (broken bone)
jerking movements or shaking
jitteriness
muscle weakness
rash on cheeks or arms that gets worse in sun
signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
sore muscles
spasms of the hands and feet
spasm of the voice box

Stop taking the medication and seek immediate medical attention if any of the following occur:

convulsions (seizures)
signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
signs of a severe skin reaction (e.g., blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with Fever or discomfort)
signs of a serious bacterial bowel inflammation or infection (e.g., severe [watery or bloody] diarrhea, fever, abdominal pain or tenderness)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Pariet (Rabeprazole).

Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Pariet (Rabeprazole).

Diarrhea: When gastric acid is decreased, the number of bacteria normally in the digestive system increases. Occasionally, this can cause serious infection in the digestive tract. If you experience watery, foul-smelling bowel movements after starting to take Pariet (Rabeprazole), contact your doctor as soon as possible.

Liver function: Liver disease or reduced liver function may cause Pariet (Rabeprazole) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Pariet (Rabeprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pariet (Rabeprazole), and whether any special monitoring is needed.

Magnesium levels: Pariet (Rabeprazole) may rarely cause low magnesium levels in people who take Pariet (Rabeprazole) for a prolonged period of time. Low magnesium may occur after at least 3 months, but usually after a year of treatment. If you have low magnesium levels in your blood, you should discuss with your doctor about how Pariet (Rabeprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pariet (Rabeprazole), and whether any special monitoring is needed.

Methotrexate interaction: Pariet (Rabeprazole), like other medications in this group, may interact with methotrexate when the two medications are used at the same time. This combination may lead to higher than expected amounts of methotrexate in the body and can cause serious side effects, including kidney damage, irregular heartbeat, Anemia, or infection. If you take Pariet (Rabeprazole), and are also going to receive a dose of methotrexate, discuss with your doctor how Pariet (Rabeprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pariet (Rabeprazole), and whether any special monitoring is needed.

More serious conditions of the stomach and intestines: If you experience symptoms of a more serious condition of the stomach and intestines (e.g., trouble swallowing, unplanned weight loss, persistent vomiting, vomiting blood, or black stools) while taking Pariet (Rabeprazole), contact your doctor immediately.

Osteoporosis fractures: Long term use of Pariet (Rabeprazole) may be related to an increased risk of bone fractures in the hip, wrist or spine, as a result of weakened bones. This risk is further increased if you are at risk of developing osteoporosis. If you have osteoporosis or have risk factors for developing osteoporosis, discuss with your doctor how Pariet (Rabeprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pariet (Rabeprazole), and whether any special monitoring is needed.

Vitamin B12: Long-term use of Pariet (Rabeprazole) may lead to vitamin B12 deficiency. If you are a vegetarian or have low vitamin B12 levels, discuss with your doctor whether any special monitoring is required.

Pregnancy: Pariet (Rabeprazole) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Pariet (Rabeprazole), contact your doctor immediately.

Breast-feeding: It is not known if Pariet (Rabeprazole) passes into breast milk. If you are a breast-feeding mother and are taking Pariet (Rabeprazole), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children and adolescents: The safety and effectiveness of using Pariet (Rabeprazole) have not been established for children and adolescents less than 18 years of age.

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