Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Nucala (Mepolizumab).
Allergic reactions: Any biologic medication such as Nucala (Mepolizumab) can cause severe allergic reactions. If you experience itching, rash, dizziness or fainting, difficulty breathing, or swelling of the throat or tongue, seek medical help immediately. These reactions usually occur soon after receiving a dose of the medication, but sometimes occur days after the dose and can occur at any time during your treatment with Nucala (Mepolizumab).
Asthma symptoms: Nucala (Mepolizumab) is not intended for use during an asthma attack. Use your reliever medications when you have an episode of wheezing or difficulty breathing.
If your asthma worsens after you start using Nucala (Mepolizumab), let your doctor know.
Infections: People using Nucala (Mepolizumab) may be at an increased risk of developing parasitic infections caused by helminths (worms). If you travel to areas where parasitic worm infections are common, discuss with your doctor how you can avoid developing these infections and what symptoms of these infections to be aware of.
Other medications: Nucala (Mepolizumab) is not intended to replace other asthma medications. Continue to use your "preventers" (long-acting bronchodilators and corticosteroids) and "relievers" (fast-acting bronchodilators) as prescribed by your doctor.
Pregnancy: Nucala (Mepolizumab) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Nucala (Mepolizumab) or less than 4 months after stopping Nucala (Mepolizumab), contact your doctor immediately.
Breast-feeding: It is not known if Nucala (Mepolizumab) passes into breast milk. If you are a breast-feeding mother and are taking Nucala (Mepolizumab), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Nucala (Mepolizumab) to treat eosinophilic asthma have not been established for children under 6 years old. The safety and effectiveness of using Nucala (Mepolizumab) to treat eosinophilic granulomatosis with polyangitis have not been established for children under 18 years old.