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Mar Pregabalin

Mar Pregabalin

(pregabalin)

Pregabalin belongs to the class of medication known as analgesics. It is used to relieve neuropathic pain associated with diabetic peripheral Neuropathy (pain from damaged nerves due to Diabetes) and postherpetic neuralgia (persisting pain following healing of the rash due to Shingles).

Available form

Dosage

Capsule

25MG, 50MG, 75MG, 150MG, 225MG, 300MG

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Mar Pregabalin information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

To treat neuropathic pain associated with diabetic neuropathy and post herpetic neuralgia, the recommended adult starting dose of pregabalin is 150 mg per day, given in 2 or 3 divided doses (e.g., 75 mg twice a day or 50 mg 3 times a day).

To treat neuropathic pain associated with the central nervous system, the recommended adult starting dose of pregabalin is 150 mg per day, given in 2 divided doses (e.g., 75 mg twice a day).

To treat pain associated with fibromyalgia, the recommended adult starting dose of pregabalin is 150 mg per day, given in 2 divided doses (e.g., 75 mg twice a day).

After one week of treatment, your doctor may increase the dose of pregabalin to 300 mg per day, given in 2 divided doses (e.g., 150 mg twice a day). The maximum recommended daily dose of pregabalin is 600 mg.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Pregabalin may be taken with food or on an empty stomach.

It is important to take Mar Pregabalin exactly as prescribed by your doctor. If you miss a dose of Mar Pregabalin by a few hours, take it as soon as possible and continue your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Mar Pregabalin at room temperature in the original packaging and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Mar Pregabalin. If you are concerned about side effects, discuss the risks and benefits of Mar Pregabalin with your doctor.

The following side effects have been reported by at least 1% of people taking Mar Pregabalin. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

Constipation
dizziness
drowsiness or sleepiness
Dry Mouth
forgetfulness
lack of energy
muscle weakness
trouble concentrating
weight gain

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

balance problems
blurred vision
cough
extreme fatigue or tiredness
signs of kidney problems (e.g., increased urination at night, decreased urine production, blood in the urine)
swelling of the extremities (hands and feet)
thoughts of harming yourself or suicide
unexplained muscle pain, tenderness, or weakness (especially if accompanied by Fever or a general feeling of being unwell)

Stop taking the medication and seek immediate medical attention if any of the following occur:

seizures
signs of a severe skin reaction such as blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort
symptoms of an allergic reaction (shortness of breath or difficulty breathing; Hives; swelling of the eyes, mouth, or throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Mar Pregabalin.

25 mg
Each opaque white/opaque white, size "4" hard gelatin capsules, radially imprinted with "A" on cap and "140" on body with black ink, filled with white-to-off-white powder, contains pregabalin 25 mg. Nonmedicinal ingredients: pregelatinized starch, and talc; capsule shell: The capsule shells contain gelatin and titanium dioxide; black ink: shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol, ammonia solution, black iron oxide, potassium hydroxide and water.

50 mg
Each opaque white/opaque white, size "2" hard gelatin capsules, radially imprinted with "A" on cap and "141" on body with black ink, filled with white-to-off-white powder, contains pregabalin 50 mg. Nonmedicinal ingredients: pregelatinized starch, and talc; capsule shell: The capsule shells contain gelatin and titanium dioxide; black ink: shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol, ammonia solution, black iron oxide, potassium hydroxide and water.

75 mg
Each opaque white/opaque orange, size "4" hard gelatin capsules, radially imprinted with "A" on cap and "142" on body with black ink, filled with white-to-off-white powder, contains pregabalin 75 mg. Nonmedicinal ingredients: pregelatinized starch, and talc; capsule shell: The capsule shells contain gelatin, red iron oxide and titanium dioxide; black ink: shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol, ammonia solution, black iron oxide, potassium hydroxide, and water.

100 mg
Each orange opaque/ orange opaque, size "3" hard gelatin capsules, radially imprinted with "A" on cap and "143" on body with black ink, filled with white-to-off-white powder, contains pregabalin 100 mg. Nonmedicinal ingredients: pregelatinized starch, and talc; capsule shell: The capsule shells contain gelatin, red iron oxide and titanium dioxide; black ink: shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol, ammonia solution, black iron oxide, potassium hydroxide, and water.

150 mg
Each opaque white/opaque white, size "2" hard gelatin capsules, radially imprinted with "A" on cap and "144" on body with black ink, filled with white-to-off-white powder, contains pregabalin 150 mg. Nonmedicinal ingredients: pregelatinized starch, and talc; capsule shell: The capsule shells contain gelatin and titanium dioxide; black ink: shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol, ammonia solution, black iron oxide, potassium hydroxide, and water.

200 mg
Each orange opaque/ orange opaque, size "1" hard gelatin capsules, radially imprinted with "A" on cap and "145" on body with black ink, filled with white-to-off-white powder, contains pregabalin 200 mg. Nonmedicinal ingredients: pregelatinized starch, and talc; capsule shell: The capsule shells contain gelatin, red iron oxide and titanium dioxide; black ink: shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol, ammonia solution, black iron oxide, potassium hydroxide, and water.

225 mg
Each opaque white/ light orange, size "1" hard gelatin capsules, radially imprinted with "A" on cap and "146" on body with black ink, filled with white-to-off-white powder, contains pregabalin 225 mg. Nonmedicinal ingredients: pregelatinized starch, and talc; capsule shell: The capsule shells contain gelatin, red iron oxide and titanium dioxide; black ink: shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol, ammonia solution, black iron oxide, potassium hydroxide, and water.

300 mg
Each opaque white/orange, size "0" hard gelatin capsules, radially imprinted with "A" on cap and "147" on body with black ink, filled with white-to-off-white powder, contains pregabalin 300 mg. Nonmedicinal ingredients: pregelatinized starch, and talc; capsule shell: The capsule shells contain gelatin, red iron oxide and titanium dioxide; black ink: shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol, ammonia solution, black iron oxide, potassium hydroxide, and water.

There may be an interaction between pregabalin and any of the following:

alcohol
angiotensin converting enzyme inhibitors (ACEIs; Captopril, Ramipril)
antihistamines (e.g., Diphenhydramine, doxylamine, Hydroxyzine)
anti-psychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
azelastine
barbiturates (e.g., butalbital, Phenobarbital)
benzodiazepines (e.g., lorazepam, Alprazolam, diazepam)
brimonidine
Buprenorphine
Buspirone
cannabis
chloral hydrate
Clonidine
diphenoxylate
efavirenz
general anesthetics (medications used to put people to sleep before surgery)
kava kava
Ketorolac
Mefloquine
Mirtazapine
Nabilone
narcotic pain relievers (e.g., codeine, Fentanyl, morphine, Oxycodone)
muscle relaxants (e.g., Baclofen, Cyclobenzaprine, methocarbamol, orphenadrine)
Orlistat
Pramipexole
Ropinirole
Rotigotine
scopolamine
seizure medications (e.g., Carbamazepine, Gabapentin, Levetiracetam, Phenytoin)
selective serotonin reuptake inhibitors (SSRIs; e.g., Citalopram, Fluoxetine, Paroxetine, Sertraline)
suvorexant
Tapentadol
thalidomide
thiazolidinediones (e.g., Pioglitazone, Rosiglitazone)
tolcapone
Tramadol
tricyclic antidepressants (e.g., Amitriptyline, Clomipramine, Desipramine, Trimipramine)
Zolpidem
Zopiclone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

stop taking one of the medications,
change one of the medications to another,
change how you are taking one or both of the medications, or
leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Mar Pregabalin. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Mar Pregabalin.

Allergic reaction: Some people have developed a serious allergic reaction called angioedema to Mar Pregabalin. Symptoms include swelling of the face, mouth (lips, gums, tongue), neck, throat, and upper airway. If these occur, seek immediate medical attention.

Central nervous system (CNS) depressants: Taking CNS depressants such as opiates (e.g., Morphine, Codeine) and benzodiazepines (e.g., Diazepam, Lorazepam) or alcohol while taking pregabalin could result in excessive sleepiness or drowsiness and even coma. Talk to your doctor if you are taking these medications.

Drowsiness/reduced alertness: Pregabalin may cause dizziness and drowsiness. Do not engage in activities requiring mental alertness, such as driving or operating machinery, until you know how Mar Pregabalin affects you.

Drinking alcohol while you are taking pregabalin may make these effects stronger. It is strongly recommended that you avoid drinking alcohol while you are taking pregabalin.

Gastrointestinal problems: Pregabalin can cause constipation. When taken with other medications that cause constipation, such as narcotic pain relievers or some antidepressants, the combination may cause blockage of the digestive system. Talk to your doctor or pharmacist for suggestions on how to manage constipation.

Heart problems: Pregabalin may cause fluid to build up in the body. If the fluid accumulates around the lungs or heart, symptoms of heart failure may become worse. If you have heart failure or other heart problems, discuss with your doctor how Mar Pregabalin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Mar Pregabalin, and whether any special monitoring is needed. Report any signs of heart problems getting worse, such as difficulty breathing, rapid weight gain or chest pain to your doctor immediately.

Kidney function: Pregabalin is primarily eliminated from the body by the kidneys. Kidney Disease or decreased kidney function may cause Mar Pregabalin to build up in the body, causing side effects. If you have reduced kidney function or kidney disease, discuss with your doctor how Mar Pregabalin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Mar Pregabalin, and whether any special monitoring is needed.

Pregabalin may reduce kidney function and can cause kidney failure. If you notice any signs of your kidneys not working well, such as decreased amounts of urine being produced, swelling of the legs and ankles, difficulty urinating, or an increased need to urinate at night, contact your doctor as soon as possible.

Male fertility: Animal studies have shown the use of pregabalin to be associated with decreased fertility, sperm abnormalities, and birth defects. It is not known if these effects would happen in people. If you plan to father a child, discuss using Mar Pregabalin with your doctor first.

Muscle pain: If you experience muscle pain, tenderness, or weakness with or without fever, contact your doctor immediately.

Skin problems: Pregabalin may cause skin ulcers or sores. Pay extra attention to your skin while taking Mar Pregabalin, especially if you have diabetes. If you notice any new skin sores or skin problems let your doctor know.

Stopping Mar Pregabalin: Stopping pregabalin suddenly may result in withdrawal symptoms such as Insomnia, nausea, headache, Diarrhea, and seizures. If it is necessary to stop taking Mar Pregabalin, talk to your doctor about the best way to reduce your dose before stopping your medication.

Suicidal behaviour: People taking Mar Pregabalin may feel that they may want to hurt themselves or others. These symptoms may occur within several weeks after starting Mar Pregabalin. If you experience these side effects or notice them in a family member who is taking Mar Pregabalin, contact your doctor immediately. You should be closely monitored by your doctor for emotional and behaviour changes while taking Mar Pregabalin.

Vision disturbances: Pregabalin may cause disturbances in your vision such as blurred vision, double vision, and vision loss. Report any changes in your vision to your doctor immediately.

Weight gain: Pregabalin may cause weight gain and swelling of the extremities. Report any significant weight gain or any swelling of the legs, arms, or other areas of the body to your doctor.

Pregnancy: Information about the safety and effectiveness of using pregabalin during pregnancy is limited. Mar Pregabalin should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Mar Pregabalin, contact your doctor immediately.

Breast-feeding: Mar Pregabalin passes into breast milk. If you are a breast-feeding mother and are taking pregabalin, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children and adolescents: The safety and effectiveness of using Mar Pregabalin have not been established for children and adolescents less than 18 years of age.

Seniors: The effectiveness of the kidneys in removing pregabalin from the body tends to decrease with age. Seniors may need lower doses of Mar Pregabalin to reduce the possibility for side effects.

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