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Dom Loperamide

Dom Loperamide

(loperamide)

Loperamide belongs to the family of medications called antidiarrheals. Loperamide, along with rehydration therapy (fluids and electrolytes), is used to treat short bouts of Diarrhea that are not caused by a bacterial infection.

Available form

Dosage

Oral Liquid

1MG/5ML, 2MG/15ML

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Dom Loperamide information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

For adults and children 12 years of age and older who have acute or chronic diarrhea, the recommended dose of loperamide is a starting dose of 4 mg, followed by a 2 mg dose after each loose bowel movement (or bout of diarrhea). Do not exceed 16 mg per day. For chronic diarrhea, once the optimal daily dose has been established, this dose can be given as a single daily dose or in divided doses.

Regular tablets should be taken with liquids. The quick-dissolve tablets can be taken without liquids. Loperamide tablets are not suitable for children under the age of 6 years old.

Children 6 to 12 years of age (10 kg to 20 kg) can use Dom Loperamide for acute or chronic diarrhea if recommended by a doctor. For children 6 to 8 years old (or weighing 20 kg to 30 kg) the recommended dose for the first day is 2 mg twice daily. For children 8 to 12 years of age who weigh over 30 kg, the recommended dose for the first day is 2 mg 3 times daily. If the diarrhea continues, then the medication is given only after a loose bowel movement, and the amount to be given depends on the weight of the child. Contact your doctor or pharmacist for the recommended amount.

For children 2 to 5 years old (or weighing 10 kg to 20 kg) the recommended dose for the first day is 1 mg 3 times daily.

For liquid forms of loperamide, use a syringe to measure each dose as this gives a more accurate measurement than household teaspoons.

Stop using loperamide if you have a solid or hard stool or if you go for 24 hours without a bowel movement. If you have acute (not chronic) diarrhea, see your doctor if it has not improved within 48 hours.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to use Dom Loperamide exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with the recommended dosing schedule (after each loose bowel movement). If it is almost time for your next dose, skip the missed dose and continue with the recommended dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Dom Loperamide at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

There may be an interaction between loperamide and any of the following:

Abiraterone
alcohol
Amiodarone
anti-psychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
"azole" antifungals (e.g., fluconazole, itraconazole, Voriconazole)
barbiturates (e.g., Phenobarbital, butalbital)
benzodiazepines (e.g., Diazepam, Lorazepam)
Carbamazepine
Carvedilol
chloroquine
Cyclosporine
Desmopressin
Dipyridamole
Disopyramide
dofetilide
Domperidone
Dronedarone
Flecainide
Gemfibrozil
macrolide antibiotics (e.g., clarithromycin, erythromycin)
Methadone
mifepristone
nefazodone
procainamide
protein kinase inhibitors (e.g., imatinib, Dasatinib, Pazopanib, Sunitinib)
quinidine
quinine
quinolone antibiotics (e.g., ciprofloxacin, Ofloxacin, sparfloxacin)
rifampin
rilpivirine
ritonavir
St John's wort
selective serotonin reuptake inhibitors (SSRIs; e.g., Citalopram, Fluoxetine, Paroxetine, Sertraline)
serotonin antagonists (anti-emetic medications; e.g., Dolasetron, Granisetron, Ondansetron)
Sotalol
tenofovir
Tetrabenazine
tricyclic antidepressants (e.g., Amitriptyline, Nortriptyline)
Verapamil

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

stop taking one of the medications,
change one of the medications to another,
change how you are taking one or both of the medications, or
leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Dom Loperamide. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Dom Loperamide.

Acquired immune deficiency syndrome (AIDS): People with AIDS should stop taking loperamide and contact their doctor if they experience abdominal swelling or distention.

Constipation: If you develop constipation, stop taking Dom Loperamide and contact your doctor.

Drowsiness or dizziness: Loperamide may cause drowsiness or dizziness. Do not drive or operate machinery until you know how loperamide affects you.

Fluids and electrolytes: The loss of fluids and electrolytes (e.g., chloride, sodium) can occur if you have diarrhea. Loperamide helps with the symptoms of diarrhea but will not correct any fluid or electrolyte problems caused by diarrhea. Talk to your doctor or pharmacist about whether you need fluid and electrolyte replacement, also referred to as oral rehydration therapy.

Improvement in diarrhea: If your diarrhea has not improved after 48 hours of treatment with loperamide, stop taking it and contact your doctor.

Liver function: Liver disease or reduced liver function may cause Dom Loperamide to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Dom Loperamide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dom Loperamide, and whether any special monitoring is needed.

Medical conditions: Loperamide should not be used by people with intestinal infections such as dysentery, which is often associated with severe diarrhea, fever, and blood in the stool, and other infections of the gut. A more serious problem of the bowel may develop if loperamide is used by some people with acute ulcerative colitis or a serious form of diarrhea associated with antibiotic use.

Pregnancy: Dom Loperamide should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Dom Loperamide, contact your doctor immediately.

Breast-feeding: Dom Loperamide passes into breast milk. If you are a breast-feeding mother and are taking loperamide, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: Dom Loperamide is not recommended for use in children under the age of 12 except on the advice of a physician. Loperamide should not be given to children under 6 years of age without medical prescription and supervision. Loperamide tablets are not suitable for children under 6 years of age. Loperamide should not be used for children under 2 years of age. (See "Who should not take Dom Loperamide.")

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All material © 1996-2024 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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