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Vyloma

Vyloma

(imiquimod)

Vyloma (Imiquimod) cream belongs to a group of medications called immune response modifiers. It works by stimulating the body's defenses to fight certain types of skin conditions.

Available form

Dosage

Cream

3.75%, 5%

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Vyloma information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

Vyloma (Imiquimod) is used by applying it to the affected area, once daily. You may apply up to 1 full actuation of the pump to the treatment area.

Before applying the cream, wash your hands with soap and water, gently wash the treatment area with mild soap and water, and allow the skin to dry thoroughly. Apply Vyloma (Imiquimod) cream to the affected skin area once a day just before going to bed. Apply a thin layer of Vyloma (Imiquimod) onto the clean, dry wart area and rub gently into skin until the cream is absorbed. Wash your hands after using the medication. Do not apply an occlusive dressing (made of airtight material) over Vyloma (Imiquimod).

Women using Vyloma (Imiquimod) to treat genital warts should be careful when applying Vyloma (Imiquimod) around the vaginal opening. Do not apply this mediation inside the vagina. If Vyloma (Imiquimod) is being used to treat perianal warts it should not be applied inside the anus.

Leave the medication on the skin area for 8 hours, and then remove it by washing the treated area with mild soap and water. Continue to use Vyloma (Imiquimod) until the warts have completely cleared, but do not use it for longer than 8 weeks. A rest period from the medication for several days may be taken depending on your discomfort and the severity of skin reactions as directed by your doctor. Treatment should not last longer than 8 weeks even if a rest period is taken.

Before using a new pump container, the pump must be primed. Remove the cap and press down on the pump one or more times until cream is dispensed. Discard this cream and then press down on the pump to get a full dose of cream.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Vyloma (Imiquimod) is for external use only. Do not take it by mouth.

It is important to use Vyloma (Imiquimod) exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and apply the cream at bedtime the next night. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Vyloma (Imiquimod) at room temperature, prevent it from freezing, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Vyloma (Imiquimod). If you are concerned about side effects, discuss the risks and benefits of Vyloma (Imiquimod) with your doctor.

The following side effects have been reported by at least 1% of people taking Vyloma (Imiquimod). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

back or joint pain
blistering on skin
burning or stinging of skin (mild)
Diarrhea
fatigue
flaking or peeling of skin
hardening of skin
headache
lightened or darkened skin colour where skin is treated
nausea
pain or irritation at the site of application
redness of skin (mild)
scabbing, crusted skin
skin itching
swelling of skin (mild)
vaginal infection (symptoms may include itching, burning, or discharge)

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

any sign or symptom in the treatment area that makes daily activity difficult or impossible
any sign or symptom that makes it difficult to continue applying the medication
difficulty urinating
flu-like symptoms (e.g., Fever or chills, headache, muscle aches, nausea)
open sores or scabs on skin
rash
skin bleeding
symptoms of an infection (e.g., coughing, sore throat, muscle or joint pain, swollen glands, fatigue)

Stop using the medication and seek immediate medical attention if any of the following occur:

signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Vyloma (Imiquimod).

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Vyloma (Imiquimod).

Immunosuppressed individuals: The safety and effectiveness of Vyloma (Imiquimod) cream has not been determined for people with medical conditions affecting the immune system (e.g., HIV/AIDS, Lupus, psoriasis) or people taking medications that reduce the effectiveness of the immune system. If you have any condition affecting the immune system, discuss with your doctor how Vyloma (Imiquimod) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Vyloma (Imiquimod), and whether any special monitoring is needed.

New genital and perianal warts: During treatment with Vyloma (Imiquimod) cream, new warts may develop, but may clear with treatment. Even though initial warts disappear with treatment, new warts may develop in the future and will require further treatment. It should be kept in mind that genital and perianal warts are considered to be a chronic condition, and Vyloma (Imiquimod) cream is not a cure.

Sexual contact: Avoid sexual contact while the cream is on your skin. The effect of Vyloma (Imiquimod) on the transmission of genital warts is unknown. Wash the medication off before sexual contact and reapply afterwards. Vyloma (Imiquimod) may weaken condoms and vaginal diaphragms; therefore, wash off Vyloma (Imiquimod) prior to using these barrier methods of birth control or use an alternate form of birth control.

Skin colour changes: Some people using Vyloma (Imiquimod) cream notice that the area where the cream was applied has become lighter or darker. Sometimes the change in skin colour is permanent.

Skin reactions: If you experience a severe skin reaction to this cream, wash the area with mild soap and water. Once the reaction has cleared, start using the cream again, unless your doctor has told you to stop using it.

Uncircumcised men: If you use Vyloma (Imiquimod) to treat warts under the penis foreskin, you should pull back the foreskin and clean the area each morning.

Pregnancy: Vyloma (Imiquimod) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Vyloma (Imiquimod), contact your doctor immediately.

Breast-feeding: It is not known if Vyloma (Imiquimod) passes into breast milk. If you are a breast-feeding mother and are taking Vyloma (Imiquimod), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Vyloma (Imiquimod) have not been established for children under 18 years of age.

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