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Uromitexan

Uromitexan

(mesna)

Uromitexan (Mesna) is used to protect the bladder against some of the harmful effects of certain cancer medications known as oxazaphosphorines (e. g.

Available form

Dosage

Injectable

100MG/ML

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Uromitexan information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

Uromitexan (Mesna) is injected into a vein through a specially prepared site on your skin. The recommended dose is usually 20% of the dose of cyclophosphamide. The injection is given at the time of a cyclophosphamide dose injection, then 4 and 8 hours later.

In the case of ifosfamide, the recommended dose is 10 mg to 12 mg per kilogram of body weight at the time of the ifosfamide dose, and 4 and 8 hours later.

Uromitexan (Mesna) may also be given by mouth under certain circumstances. When this is the case, the dose may be higher than those suggested here.

Uromitexan (Mesna) may also be given to people being prepared for bone marrow transplantations. Under these circumstances, the doses may be given around the clock for a brief period of time.

Many things can affect the dose and schedule of medication that a person needs, such as body size, other medical conditions, and other medications. Your doctor may choose a different dose or schedule than the ones listed here. Uromitexan (Mesna) is always given under the direct supervision of your doctor.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Uromitexan (Mesna). If you are concerned about side effects, discuss the risks and benefits of Uromitexan (Mesna) with your doctor.

The following side effects have been reported by at least 1% of people taking Uromitexan (Mesna). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

abdominal pain
Diarrhea
flushing
headache
lightheadedness
nausea
redness or irritation at the infusion site
skin rash
unusually sleepy during the day

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

fast heart rate
Fever
flu-like symptoms (e.g., sore throat, fever, chills, shivering, cough, body aches)
severe dizziness
signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)

Stop taking the medication and seek immediate medical attention if any of the following occur:

chest pain
signs of a serious allergic reaction (i.e., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
signs of a severe skin reaction such as blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Uromitexan (Mesna).

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All material © 1996-2024 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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