The usual recommended dose of Synarel (Nafarelin) nasal spray is one spray (200 µg) into one nostril in the morning, and one spray into the other nostril in the evening, for a total daily dose of 400 µg. The doses should be approximately 12 hours apart. Some women may require higher doses (e.g., 800 µg per day).
Treatment should be started between the second and fourth day after the beginning of menstrual bleeding. During the first 2 months of using Synarel (Nafarelin), vaginal bleeding, also known as breakthrough bleeding, may occur. The length of treatment is usually for 6 months, unless otherwise instructed by your doctor.
Ask your doctor or pharmacist to teach you the proper way to use this nasal spray. If you are using Synarel (Nafarelin) for the first time or using a new bottle of Synarel (Nafarelin) you will need to prime the spray pump. To prime the spray pump, turn the tip of the bottle away from you, put 2 fingers on the "shoulders" of the spray bottle and put your thumb at the bottom of the bottle, and push down 7 to 10 times until you see a fine mist appear.
Gently blow your nose to clear your nostrils before each use. If you sneeze during or immediately after the dose, contact your doctor or pharmacist for advice.
After each use, clean the spray tip by holding the bottle in a horizontal position and rinsing the spray tip with warm water while wiping the tip with your finger or a soft cloth for approximately 15 seconds.
If you are using another nasal spray (e.g., a decongestant spray), wait 30 minutes after using Synarel (Nafarelin) nasal spray before using the other nasal spray.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use Synarel (Nafarelin) exactly as prescribed by the doctor. For Synarel (Nafarelin) to be effective, it must be used regularly without interruption (e.g., no missed doses). If you miss a dose of Synarel (Nafarelin), contact your doctor or pharmacist for advice. Do not take a double dose to make up for a missed one.
Store Synarel (Nafarelin) at room temperature in an upright position, protect it from light, and keep it out of the reach of children. Do not freeze the medication.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.