The usual dose of Pulmozyme (Dornase-alfa) is one 2.5 mg ampule inhaled once a day using the recommended nebulizer. Some people may use Pulmozyme (Dornase-alfa) twice a day if recommended by their doctor.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are
taking the medication without consulting your doctor.
It is important to use Pulmozyme (Dornase-alfa) exactly as prescribed by your doctor and that you understand how to use and maintain the nebulizer. Read the patient instructions provided and talk to your doctor or pharmacist if you are not sure how to use Pulmozyme (Dornase-alfa) properly. Use the nebulizer and mouthpiece that is recommended or provided to you. Do not mix Pulmozyme (Dornase-alfa) with any other medication in the nebulizer. Before using an ampule, squeeze it to ensure it does not leak. Pulmozyme (Dornase-alfa) contains no preservative and once an ampule is opened, the entire content must be used or discarded.
If you miss a dose, use it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Pulmozyme (Dornase-alfa) in the refrigerator, protect it from light, and keep it out of the reach of children.
Pulmozyme (Dornase-alfa) should be kept refrigerated during travelling and should not be at room temperature for more than 24 hours. If you notice that the solution is cloudy or discoloured, do not use it and discard it.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.