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Luveris

Luveris

(lutropin-alfa)

Lutropin alpha belongs to the class of medications called gonadotropins. Lutropin alpha contains the human hormone luteinizing hormone (LH).

Available form

Dosage

Injectable Powder

75IU

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Luveris information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The usual dose of lutropin alpha is 75 IU injected under the skin daily, around the same time each day. Treatment usually lasts for 14 days or less.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Your doctor or health care professional will show you how to inject Luveris (Lutropin-alfa) properly. Luveris (Lutropin-alfa) can be mixed in the same syringe as Gonal-f® (follitropin alpha) and given as one injection.

Once the dose of medication has been prepared, it should be used immediately. Discard any unused material after use. Do not use your injectable solution if it appears cloudy, lumpy, or discoloured. Read the patient information carefully and ask your doctor or health care professional any questions you may have.

It is important that you follow the dosing schedule closely and that you keep all doctor's appointments. Your doctor will monitor how your ovaries are responding to the medication and frequent appointments will be necessary. If you miss a dose of Luveris (Lutropin-alfa), contact your doctor to see when your next dose should be given.

Store Luveris (Lutropin-alfa) at room temperature or in the refrigerator (2°C to 25°C), protect it from light, and keep it out of the reach of children. Do not expose to extreme heat or cold.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who uses Luveris (Lutropin-alfa). If you are concerned about side effects, discuss the risks and benefits of Luveris (Lutropin-alfa) with your doctor.

The following side effects have been reported by at least 1% of people using Luveris (Lutropin-alfa). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

breast tenderness
Constipation
drowsiness
fatigue
headache
nausea, vomiting, or Diarrhea (not continuing or severe)
pain, redness, itching, swelling at the place of injection
painful menstruation

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Stop using the medication and seek immediate medical attention if any of the following occur:

signs of a blood clot in blood vessels (e.g., difficulty breathing, chest pain, pain and swelling in one leg muscle)
signs of a Anaphylaxis (severe allergic reaction) (e.g., difficulty breathing; Hives; swelling of the mouth, tongue, or throat)
signs of Stroke (sudden trouble with vision, dizziness, sudden severe and unusual headache, weakness, difficulty speaking)
symptoms of ovarian hyperstimulation syndrome:
- abdominal or pelvic discomfort or pain
- decreased urination
- diarrhea
- difficulty breathing
- nausea
- rapid weight gain
- vomiting

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Luveris (Lutropin-alfa).

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Luveris (Lutropin-alfa).

Blood Clots: Luveris (Lutropin-alfa) may increase the chance of blood clot formation causing a reduction of blood flow to the extremities. If you have a history of clotting you may be at increased risk of experiencing blood clot-related problems such as Heart Attack, stroke, or clots in the deep veins of your leg. Discuss with your doctor how Luveris (Lutropin-alfa) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Luveris (Lutropin-alfa), and whether any special monitoring is needed.

If you experience symptoms such as sharp pain and swelling in the leg, difficulty breathing, chest pain, blurred vision or difficulty speaking, contact your doctor immediately.

Multiple births: Multiple births may occur with fertility medications. Talk to your doctor about the risks of multiple births before beginning treatment.

Ovarian enlargement: Some women using Luveris (Lutropin-alfa) may experience ovarian enlargement associated with abdominal bloating or pain. In most cases, these symptoms go away without treatment within 2 or 3 weeks. If you experience these symptoms contact your doctor.

Ovarian hyperstimulation syndrome (OHSS): Treatment with Luveris (Lutropin-alfa) can cause a condition called ovarian hyperstimulation syndrome (OHSS). With OHSS, too many follicles grow and cause abdominal or pelvic discomfort or pain, nausea, vomiting, and weight gain. Some women may experience difficulty breathing and diarrhea. OHSS can progress rapidly and may become serious. If you experience any of these symptoms, contact your doctor immediately.

Pregnancy: The effect of lutropin alpha on an unborn baby is unknown. To avoid the possibility of harm to the baby, Luveris (Lutropin-alfa) should not be used during pregnancy.

Breast-feeding: It is not known if lutropin alpha passes into breast milk. If you are a breast-feeding mother and are taking Luveris (Lutropin-alfa), it may affect your baby. Do not breast-feed while you are taking Luveris (Lutropin-alfa).

Children: Luveris (Lutropin-alfa) is intended for use by women of child-bearing age. Its safety and effectiveness have not been established for children.

Seniors: Luveris (Lutropin-alfa) is intended for use by women of child-bearing age. Its safety and effectiveness have not been established for seniors.

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