Galafold

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Galafold (Migalastat). If you are concerned about side effects, discuss the risks and benefits of Galafold (Migalastat) with your doctor.

The following side effects have been reported by at least 1% of people taking Galafold (Migalastat). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• abdominal pain
• appetite changes
• arm, leg, back, or neck pain
• balance problems, unsteadiness
• changed patches of skin pigmentation
• changed sense of touch
• chest discomfort
• Diarrhea
• dizziness
• Dry Mouth
• feeling hot
• flu-like symptoms (e.g., body aches, fatigue, Fever)
• frequent urination
• hair loss
• headache
• heartburn
• itchy eyes
• memory problems
• migraine
• muscle pain, spasms
• muscular chest pain
• nausea
• night sweats
• nosebleeds
• pins and needles in hands or feet
• psoriasis (red, itchy, scaly patches of skin)
• runny nose
• skin rash or redness
• sneezing
• spinning sensation
• sweating
• tiredness
• trouble sleeping
• vision changes
• vomiting
• weight changes

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• aggressiveness, feeling impatient
• blood in the stools
• breathing problems
• enlarged Thyroid gland (swelling at the front of the neck)
• fast, pounding heartbeat
• high blood pressure
• irritable bowel syndrome (e.g., stomach pain or cramping, bloating, diarrhea or Constipation, excessive gas)
• lack of muscle coordination
• low blood sugar (e.g., cold sweat, cool pale skin, headache, fast heartbeat, weakness)
• movement disorders (e.g., unintended muscle movement, decreased coordination, tremor)
• puffiness in arms, legs, ankles, weight gain
• signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
• signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
• swelling feet and legs
• symptoms of gallstones (e.g., intermittent, severe, dull pain in the upper right part of the abdomen; nausea; vomiting; intolerance of fatty or greasy foods)
• symptoms of a urinary tract infection (e.g. pain when urinating, urinating more often than usual, low back or flank pain)
• urine cloudiness, foaming urine

Stop taking the medication and seek immediate medical attention if any of the following occur:

• irregular heartbeat (e.g., fast, pounding heartbeat, fainting, lightheadedness, shortness of breath)
• lack of oxygen to heart muscle, signs of Heart Attack (e.g., sudden chest pain or pain radiating to back, down arm, jaw; sensation of fullness of the chest; nausea; vomiting; sweating; anxiety)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Galafold (Migalastat).