Wash the area to be treated with soap and water, then dry the area thoroughly. Apply the cream to the affected area twice a day with a nonmetal applicator (e.g., a cotton swab) or while wearing a suitable glove. Apply a thin layer, enough to cover the entire affected area of the skin. If fingertips are used to apply, wash your hands well with soap and water immediately afterwards.
Avoid contact with the eyes, eyelids, corners of the nose and mouth, easily irritated areas, or other areas where treatment is not intended. If you apply the medication near the eyes, nose, or mouth, take care to avoid getting the medication in these sensitive areas.
Efudex (Fluorouracil-topical) will cause the skin to become severely inflamed and irritated, but continue to use it for the length of time recommended by your doctor, usually for 2 to 4 weeks. Complete healing of the treated area may take 1 to 2 months after stopping treatment. If the area becomes severely irritated, contact your doctor.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use Efudex (Fluorouracil-topical) exactly as prescribed by your doctor. If you miss a dose, apply it as soon as possible and continue with your regular schedule. If more than a few hours have passed, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one. If you are not sure what to do after missing a dose, or you have missed more than one dose, contact your doctor or pharmacist for advice.
Store Efudex (Fluorouracil-topical) at room temperature and protect it from light, heat, and moisture. Keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.