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Desipramine

Desipramine

(desipramine)

Desipramine belongs to the class of medications known as tricyclic antidepressants. Desipramine helps to elevate mood and eliminate or reduce other symptoms associated with Depression.

Available form

Dosage

Tablet

10MG, 25MG, 50MG, 75MG, 100MG

Buy Desipramine Full drug details

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Desipramine information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

For the treatment of depression in adults, the recommended starting dose of desipramine is 75 mg in divided doses, with or without food. This dose is usually increased gradually until the most effective dose is found. The usual adult dose is 100 mg to 200 mg daily. Doses above 300 mg daily are not recommended. It may take several weeks before the medication has its full effect so you should be patient with the results.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Desipramine exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue on with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Desipramine at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Desipramine. If you are concerned about side effects, discuss the risks and benefits of Desipramine with your doctor.

The following side effects have been reported by at least 1% of people taking Desipramine. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

abdominal cramps
blurred vision
Constipation
difficulty urinating
dizziness when getting up from a sitting or lying position
drowsiness
dryness of mouth or eyes
excitement
headache
increased or irregular heart rate

irritability
itchy skin
muscle twitching
nausea
rash
sexual dysfunction
sweating
tiredness or weakness
trouble sleeping
vomiting
weight gain

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

anxiety
blurred vision
breast enlargement (both males and females)
confusion or delirium
constipation (especially for seniors)
difficulty speaking or swallowing
eye pain
fainting
fast or irregular heartbeat (pounding, racing, skipping)
hair loss
hallucinations
inappropriate secretion of milk (females)
increased sensitivity to sunlight
loss of balance control
muscle twitching
nervousness or restlessness

numbness or tingling sensation in arms and legs
red or brownish spots on skin
ringing, buzzing, or other unexplained sounds in the ears
seizures
shakiness or trembling
shuffling walk
skin rash and itching
slowed movements
stiffness of arms and legs
sore throat and Fever
swelling of face and tongue
swelling of testicles
trouble with teeth or gums
yellow eyes or skin

Stop taking the medication and seek immediate medical attention if any of the following occur:

symptoms of a Anaphylaxis (severe allergic reaction) such as swelling of the mouth or throat, chest tightness, or shortness of breath

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Desipramine.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Desipramine.

Diabetes: Both elevation and lowering of blood sugar levels have been reported with desipramine use. People with diabetes or Hypoglycemia (low blood sugar) should monitor their blood glucose levels closely while taking Desipramine.

Drowsiness/reduced alertness: Desipramine may reduce the mental or physical abilities required for the performance of hazardous tasks, such as operating machinery or driving a motor vehicle. Use appropriate caution until you determine how Desipramine affects you.

Heart rhythm: Desipramine can cause abnormal heart rhythms, particularly when taken in high doses. Therefore, seniors and those with a history of heart disease should take desipramine with caution.

Medical conditions: If you have Thyroid disease, a history of seizures, mania (desipramine may induce mania in people with a history of mania or bipolar disorder), urinary retention, narrow-angle Glaucoma, or increased eye pressure, discuss with your doctor how Desipramine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Desipramine, and whether any special monitoring is needed.

Suicidal thoughts: Desipramine may increase the risk of suicidal thoughts, especially when starting therapy or adjusting the dosage. Seek medical attention if there are any signs of worsening condition.

Pregnancy: Desipramine should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Desipramine, contact your doctor immediately.

Breast-feeding: Desipramine passes into breast milk. If you are a breast-feeding mother and are taking desipramine, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Desipramine have not been established for children.

Seniors: Seniors should use Desipramine with caution, and should not exceed the recommended dose.

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