Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Resotran (Prucalopride).
Abnormal heart rhythm: Resotran (Prucalopride) has been shown to cause increased heart rate and may contribute to an irregular heartbeat. If you have a history of irregular heartbeat or ischemic heart disease, discuss with your doctor how Resotran (Prucalopride) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Resotran (Prucalopride), and whether any special monitoring is needed.
Bowel inflammation: Resotran (Prucalopride) may cause a potentially dangerous condition known as ischemic colitis. This occurs when not enough blood is reaching the walls of the colon. Symptoms include abdominal pain; severe, watery diarrhea that may be bloody; or bleeding from the rectum. If you notice these symptoms, stop taking Resotran (Prucalopride) and seek immediate medical attention.
Drowsiness/reduced alertness: Resotran (Prucalopride) may cause dizziness or tiredness when you first start to take it. Do not drive, operate machinery, or perform other hazardous tasks until you have determined how Resotran (Prucalopride) affects you.
Liver function: There is very little information about how Resotran (Prucalopride) is affected by reduced liver function. If you have liver problems or reduced liver function, discuss with your doctor how Resotran (Prucalopride) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Resotran (Prucalopride), and whether any special monitoring is needed. If you have severely reduced liver function you may need a lower dose.
Kidney function: Reduced kidney function or kidney disease may cause Resotran (Prucalopride) to build up in the body, causing side effects. If you have reduced kidney function or kidney disease, discuss with your doctor how Resotran (Prucalopride) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Resotran (Prucalopride), and whether any special monitoring is needed.
A lower-than-usual dose is recommended for people with severely reduced kidney function. If you have kidney disease that requires dialysis you should not take Resotran (Prucalopride).
Mental health: In clinical trials of people taking Resotran (Prucalopride) there were reports of mood or behavior changes, including suicide. People taking Resotran (Prucalopride) may experience changes in mood or behavior, worsening depression, or they may want to hurt themselves or others. If you experience these side effects or notice them in a family member who is taking Resotran (Prucalopride), contact your doctor immediately.
Pregnancy: There is not enough information available at this time to determine the safety and effectiveness of using Resotran (Prucalopride) during pregnancy. Resotran (Prucalopride) should be avoided by women who are pregnant.
Women of childbearing age who are taking Resotran (Prucalopride) should use an effective method of birth control (e.g., birth control pill, condoms) during treatment. If you become pregnant while taking Resotran (Prucalopride), contact your doctor immediately.
Breast-feeding: Resotran (Prucalopride) passes into breast milk. If you are a breast-feeding mother and are taking Resotran (Prucalopride), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Resotran (Prucalopride) have not been established for children less than 18 years of age.
